Guyton

Question 1

Name the 3 main ions in the intracellular fluid

Answer 1

Mg, K, phosphate

Question 2

Where are the baroreceptor located?

Answer 2

Bifurcation of the carotide in the neck

Arch of the aorta

Question 3

Endoplasmic reticulum synthesize _______ in the granular part and ______ in the agranular part

Answer 3

Proteins

Lipids

Question 4

What is contained in lysozyme for bactericidal?

Answer 4

Lysozyme (dissolve bacterial wall)
Lysoferrin (binds iron)
Acid hydrolase

Question 5

Functions of the Golgi?

Answer 5

Process substance formed in the ER, synthesize carbohydrates, secretary vesicles

Question 6

Transcription

Answer 6

DNA into RNA

In nucleus

Question 7

Translation

Answer 7

RNA into proteins

In cytosol

Question 8

3 types of RNA and their function

Answer 8

1- Messenger (carries genetic code into cytoplasm for proteins production)

2- transfer (attach amino acid to the ribosomes)

3- ribosomal (physical structure in cytoplasm on which proteins are synthesize)

Question 9

Cell apoptosis is initiate by which enzyme ?

Answer 9

Cascade

Question 10

Functions of red blood cells

Answer 10

• transport hemoglobin
• contains carbonic anhydrase
• acid base buffer

Question 11

Production of RBC controlled via

Answer 11

Il-3
Hypoxia-inducible factor
EPO ( 90% in kidneys, 10% in liver)

Question 12

Life span of RBC

Answer 12

120 days

Question 13

Lifespan of platelets ?

Answer 13

10 days

Question 14

Which part of the complement is involve in opsonization ?

Answer 14

C3

Question 15

Explain neutrophils migration in response to chemotaxis molecules?

Answer 15

1) cytokines increases adherence molecules ( selectin and intercellular adhesion molecule 1)
2) margination (react with integrin on neutrophils)
3) diapedesis ( endothelial cells loosen)

Question 16

What 2 cells release eosinophils chemotactic factor?

Answer 16

Mast cell

Basophils

Question 17

Which IL is secreted by macrophages to promote reproduction of specific lymphocytes?

Answer 17

Il-1

Question 18

Which lymphocytes participates in humoral immunity?

Answer 18

B

Question 19

Which lymphocytes participates in cell mediated immunity?

Answer 19

T

Question 20

Which is the predominant immunoglobulin?

Answer 20

IgG

Question 21

Which part of the complement participates in:

• opsonisation and phagocytosis
• cell lysis
• chemotaxis
• activation of mast cell and basophils

Answer 21

• C3b
• C5b6789
• C5a
• C3a, C4a, C5a

Question 22

Which cells have MCH?

Answer 22

Macrophages, b lymphocytes and dendritic cells

Question 23

To which cells MHC I and II presents?

Answer 23

I- cytotoxic T

II- T helper

Question 24

Which IL activates cytotoxic T cell?

Answer 24

IL-2

idem than Treg

Question 25

Which immunoglobulin are involve in transfusion mismatch?

Answer 25

IgG and IgM