gut acid secretion Flashcards

1
Q

how do antacids work

A

these are good for mild acid reflux and they serve to neutralise the stomach acid secreted

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2
Q

how do proton pump inhibitors work

A

these inhibit the H+/K+ ATPase pumps at the cell lumen to inhibit acid secretion - omeprazole
these are activated by the stomach acid secretions themselves, take 30 minutes before food

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3
Q

how does an antihistamine work for gut acid secretion

A

cimetidine, this inhibits stimulation of acid secretion by histamine which would normally increase secretions in the parietal cell

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