Guinea-pigging Flashcards
What did this study consists of
a fiber optic tube inserted in their mouths and down their esophaguses so they could examine the G.I. tract
where did most drug studies take place in and where do they take place now?
medical schools and teaching hospitals now more than 75% are performed in the private sector
what phase are most professional guinea pigs involved in
phase 1 which tests the safety of the drug
How did illegal immigrants get recruited for a trial without getting caught.
Because they had to be approved by a a I.R.B. and the non profit ones were in universities and teaching hospital however this trial was not in any of these. So there are for profit I.R.B. and they must compete for income.
What does I.R.B. stand for?
institutional review board
what year did the FDA receive a code number for reporting “failure to protect rights, safety and warfare of subjects
2005
Guinea pigs rely on who to determine if studies are safe
their wits or by word of mouth
Which trials do the Guinea pigs tend to stay away from?
heart drugs and psychiatric drugs
what happened in 2006 at the north wick park hospital outside london when a _____ antibody was being tested….
monoclonal antibody
-6 of the volunteers where rushed to the hospital due ti severe inflammation and organ failure. one person had fingers/toes amputated while the others have long term disabilities.
why did faruk abuzzahab need to take a medical ethics class.
what was his first reason and what was his real reason.
first-the state licensing board ordered him to take this class because there was trouble in a research study
truth-it was a disciplinary action due to injuries or death of 46 patients and the patients were not healthy subjects.
what was abuzzahab’s awarded in 2003 from the american psychiatric association
distinguished life fellowship
what percent of medical centers provided free care to those who were injured due tot he study
16 percent
Who were most of the patients in the large Miami site for doing phase 1 human drug trials?
illegal immigrants
What sort of clientele predominated at Eli Lilly’s Indianapolis drug trial site?
homeless alcoholics
Discuss some of the unsavory details of some of the patient recruiters.
held money, terrible conditions, don’t pay for care
