GU surgery Flashcards
kidneys lie retroperitoneally in the abd at what 2 levels?
T12 and L4
renal arteries originate from what artery?
aorta
renal veins cross anteriorly or posteriorly before joining the IVC?
anteriorly
renal innervation is primarily sympathetic and afferent fibers that arise from what range of spinal levels?
T10-L1
surgical anesthesia of the kidneys requires what range of levels?
T8-L3
kidney pain may be perceived by afferent fibers that travel in what nerve? (V)
vagus nerve
what level of sensory block is needed to produce anesthesia for the ureters?
T10
The long what of ureters makes them vulnerable to injury/transection during retroperitoneal surgery? (P)
path
should LA containing epi be given for injections around the penis?
no
what response may occur with testicular manipulation? (V)
vagal response
what 5 things make up the urinary system? (K,BS,U,B,U)
kidneys, blood supply, ureter, bladder, urethra
what % range of the CO goes to the kidneys?
20-25%
what is the renal BF equation?
RBF=(MAP-VP)xVR
what 2 things determine renal BF? (NA, NR)
natural autoregulation, neural regulation
what is the MAP range to maintain renal filtration?
50-180 mmHg
MAP less that what stops filtration?
<50 mmHg
renal BF to both kidneys is how many mLs per minute?
1200 mL
glomerular filtration is the filtering the blood into tubule forming what? (PU)
primitive urine
tubular reabsorption is absorption of substances needed by the body from what to what?
from the tubule to the blood
tubular secretion is the secretion of substances to be eliminated from where to where?
blood to the tubule
AKI is up to what % of critically ill pts?
8%
what are 10 preop risk for AKI? (EKD,D,H,H,LD,I,T,M,A,NAE)
existing kidney disease, DM, HTN, hypovolemia, liver disease, infection, trama, MM, age (>55), nephrotoxic agent exposure
Prerenal, intrinsic or postrenal AKI:
- impaired renal autoregulation
- decrease effective circulating volume
- acute glomerulonephritis
- vasculitis
- bladder outlet obstruction
- prerenal
- prerenal
- intrinsic
- intrinsic
- postrenal
what are the 3 most important prophylactic measures to avoid AKI? (MNRP, AN, APH)
maintain normal renal perfusion, avoid nephrotoxins, avoid prolonged hypoperfusion
what procedures can significantly alter renal function? (L, CB, ACC, RAD, NP)
laparoscopy, CPB, aorta cross clamping, renal artery dissection, neurosurgical procedures
are anesthesia effects on the kidneys more or less during regional anesthesia?
less
what are the 3 reversible anesthesia effects on normal RBF? (H, SA, EE)
hypotension, sympathetic activation, endocrine effects
light anesthesia and intense surgical stimulation causes what reversible anesthesia effect on normal RBF? (SA)
sympathetic activation
hypotension limits what that ends up reducing renal function? (A)
autoregulation
Response to what causes the endocrine effects that causes an increase in catecholamines and a decrease in renal BF? (S)
stress
ADH and angiotensin 2 decrease RBF by causing constriction where? (RA)
renal artery
what VA that is not used anymore has high nephrotoxicity? (M)
methoxyflurane
do isoflurane and desflurane produce nephrotoxicity?
no
sevoflurane has the potential for nephrotoxicity from having what as its byproduct? (CA)
compound A
what electrolyte are we worried about with renal pts?
potassium
what is the GFR equation?
urine cr x serum cr x urine volume
normal range of lab values:
- BUN (mg/dL)
- serum Cr (mg/dL)
- creatinine clearance (mL/min)
- 10-20 mg/dL
- 0.7-1.5 mg/dL
- 95-150 mL/min
what lab test is the main product of protein metabolism?
BUN
what lab test is a key indicator for GFR function?
serum Cr
what test is considered the specific test for GFR?
Cr clearance
what test measures the ability of the glomeruli to excrete creatinine given a specific plasma creatinine concentration?
Cr clearance
what 3 lab tests measure renal tubular function? (USG, UO, USC)
- urine specific gravity
- urine osmolality
- urine sodium concentration
Is urine specific gravity or urine osmolality more specific of renal tubular function?
urine osmolality
normal range of lab values:
- urine specific gravity
- urine osmolality (mOsm/L)
- urine sodium concentration (mEq/day)
- 1.003-1.030
- 65-1400 mOsm/L
- 130-260 mEq/day
urine specific gravity and urine osmolality measure waht in urine? (S)
solutes
What GFR range for these CKD stages? (mL/min/1.73 m^2)
- stage 1
- stage 2
- stage 3
- stage 4
- stage 5
- > 90
- 60-89
- 30-59
- 15-29
- <15
Qualitatively describe the CKD stages:
- stage 1
- stage 2
- stage 3
- stage 4
- stage 5
- normal
- mild
- moderate
- severe
- ESRD
Risk criteria:
- Cr increased how many times?
- GFR decreased greater than what %?
- UO less than what for how many hrs?
- 1.5 times
- 25%
- .5 mL/kg/hr for 6 hrs
Injury criteria:
- Cr increased how many times?
- GFR decreased greater than what %?
- UO less than what for how many hrs?
- 2 times
- 50%
- .5 mL/kg/hr for 12 hrs
Failure criteria:
- Cr increased how many times?
- GFR decreased greater than what %?
- Cr greater than what? (mg/dL
- UO less than what for how many hrs?
- 3 times
- 75%
- 4 mg/dL
- .3 mL/kg/hr for 24 hrs (or anuric for 12 hrs)
Loss criteria is complete loss of renal function greater than how many weeks?
4 weeks
Renal failure system abnormalities:
- hyper or hypokalemia?
- hyperparathyroidism or hypoparathyroidism?
- hypernatremia or hyponatremia?
- hypercalcemia or hypocalcemia?
- hyperkalemia
- hyperparathyroidism
- hypernatremia
- hypocalcemia
what are 5 causes of chronic renal failure? (DN, H, G, PKD, KI/O)
- diabetic neuropathy
- HTN
- glomerulonephritis
- polycystic kidney disease
- kidney infection/obstructions
Chronic renal failure:
- what is the mortality %?
- what % will need dialysis?
- 20%
2. 50%
do pts with renal disease have delayed gastric emptying?
yes