GU Flashcards
Urinary Tract System
kidneys, ureters, bladder (2 sphincters: internal & external/voluntary) and urethra
Kidneys (anatomy)
- cortex is outside (contains glomeruli)
- medulla is inside (tubular & collecting ducts)
- glomerulus (encapsulated capillaries aka filtration membranes, allows components of the blood to filter through)
- afferent arteriole (blood enters here; dilates)
- juxtaglomerular apparatus (supplies blood to glomeruli & detects changes in BP)
Pediatric urinary output
1mL/kg/hour
Adult urinary output
1 liter per day
Crystalloid fluid
- capable of passing thru a semipermeable membrane as in dialysis
- 1st choice in rapid volume replacement given in IV bolus of 10-20 mL/kg over 10 -15 minutes
- An increase in BP and decrease in HR indicate successful resuscitation
- LR & 5% dextrose
Colloid fluid
- not capable of passing thru a semipermeable membrane
- contains protein
- remains in vascular space longer than crystalloids
- often administered to children in shock
- albumin
Whole blood
- used only in incidents of known blood loss
- active bleeding or markedly decreased hematocrit
Fresh frozen plasma (FFP)
- used to correct coagulopathies
- not for volume replacement
Hemodialysis
- preferred method in most cases because protein loss less extensive than with peritoneal dialysis
- difficult in children less than 20 kg
- done via graft, fistula, or external access device
- preferred site is radial artery and forearm vein
- usually 3x/wk for 3-5 hours
- outpatient or hospital or dialysis facility
- home hemodialysis ideal for children waiting for transplants, living far from medical facilities, or those who have had more than one kidney transplant failure.
Peritoneal dialysis
- for acute conditions
- quick & relatively easy to learn, safe to perform & requires minimum equipment/nurses
- slow, gentle process decreased pressure on organs
- great for limited vascular access, children with cardiac disease and neonates
- fewer dietary restrictions
- most often performed at home
- contraindicated for recent abdominal surgery, adhesion or scarring
- higher rate of infection
Continuous venovenous hemofiltration
- used in acute care settings
- filtrates blood using special equipment at a very low setting
- fluid balance may be achieved within 24-48 hours
- used to remove excess fluid from patients with severe oliguria fluid overload
- successful in children who might not survive the rapid volume exchanges of hemodialysis and peritoneal dialysis
Chronic renal disease and electrolyte imbalances
- potassium elevated
- phosphorus elevated
- calcium decreased
Urinary tract infections
- inflammation, usually bacterial in origin, of the urethra (urethritis), bladder (cystitis), ureters (ureteritis), or kidneys (pyelonephritis)
- most common organism E. coli (80%)
- peak incidence, not structural, is 2-6 years old
- females have a 10-30x higher risk r/t shorter urethra (5-6% have first UTI by 1st grade)
Intrinsic factors r/t UTI
- urine stasis (most important contributing factor), reflux, constipation, pregnancy
- neurogenic bladder
Extrinsic factors r/t UTI
- poor hygiene, tight clothing/diapers, catheters, constipation, pregnancy
- antimicrobial agents
- bubble baths
Altered urine and bladder chemistry r/t UTI
-decreased fluid intake
Pathophysiology of UTI
- recurrent cystitis may produce anatomic changes in the ureter that leads to vesicoureteral valve incompetence and reflux of urine
- pyelonephritis can lead to acute and chronic inflammatory changes in the pelvis and medulla with scarring and loss of tissue
- recurrent or chronic infections results in increased fibrotic tissue
- controversy remains on whether or not cranberry juice helps prevent bacteria from sticking to bladder wall
Clinical manifestations of UTI
- may be asymptomatic or nondescript symptomatology
- newborn - 2 yrs: fever or hypothermia, vomiting, FTT, abdominal distention, diarrhea, jaundice ( under 2 can’t concentrate their urine r/t immature renal function), may also have persistent diaper rash
- 2 to 12 yrs: enuresis, incontinence in a child previously not, fever, strong or foul-smelling urine, increased frequency, urgency
- adolescent: flank pain, fever, hematuria
Goals of treatment with UTI
- guided by culture and sensitivity
- eliminate current infection –> antibiotic therapy
- identify contributing factors to reduce relapse –> parent teaching
- prevent urosepsis
- preserve renal function
Diagnostic evaluation r/t UTI
- Urine culture (clean catch, catheter, suprapubic tab)
- suprapubic tap 1,000
- catheter >10,000 indicates UTI
- clean catch >100,000 indicates UTI
- ultrasonography
- voiding cystourethrogram (VCGU)
- intravenous pyelogram (IVP)
- dimercaptosuccinic acid scan (DMSA)
Vesicoureteral reflux (VUR)
- retrograde flow of bladder, urine up the ureters
- primary reflux results from congenital abnormalities in insertion of ureters into the bladder; siblings need screened as there is a 36% chance they will have it as well (<2 yrs)
- secondary reflux results from UTI infections/stasis in the bladder and ureterovesicular junction incompetency due to edema, neurogenic bladder, dilation of ureters following surgical urinary diversion
Pathophysiology of VUR
- it occurs when the pressure of a full bladder forces urine into the upper urethra
- as pressure is decreased, urine refluxes into the ureter, predisposing the child to UTI’s
- simple UTIs that begin in the bladder via an ascending urethral route are transmitted to the upper urinary tracts and kidney
- classified according to the degree of reflux (graded 1-5; grade 4-5 significant and warrant surgery with significant anatomic anomaly resulting in frequent UTIs or child from noncompliant family)
- important cause of renal damage; refluxed uring ascending into the collecting tubules of nephrons gives microorganisms access to the renal parenchyma, causing scaring
- reflux causing scarring will lead to loss of functioning nephrons and some degree of compromised function
- affects kidney growth
Nursing considerations with VUR
- Tx with low dose antibiotics w/ frequent ua cultures
- parent education r/t medication administration
- parent teaching r/t collection of urine specimen
- preoperative teaching (antibiotics)
- postoperative care (cont. antibiotics, schedule renal US to r/o obstruction month out, d/c antibiotics if no obstruction, US and cystograms sometimes scheduled 6 months out but require catheter so some don’t like to do them and risk reintroducing bacteria.)
Glomerulonephritis
A term that includes a variety of disorders, most of which are caused by an immunological reaction. It results in proliferative and inflammatory changes within the glomerular structure and destruction, inflammation, and sclerosis of the glomeruli of both kidneys.