GTR Flashcards
GTR requires a regeneration of what tissues to be successful?
cementum, PDL, alveolar bone in a previously diseased site.
What must you do before GTR?
STOP perio dz
Is GTR a treatment for perio dz?
NO - it just regenerates the defective tissue caused by perio dz
Define Repair:
wound healing by tissue that does not fully restore the architecture of the diseased part
Define Reattachment:
reunion of epithelial and CT w root surface and bone
Define New attachment:
union of CT or epi w the root that has been deprived of its original perio attachment.
How might something obtain new attachment?
epithelial adhesion, CT adaptation, or attachment and new cementum formation
Define bone fill:
reformation of all/part of bone in perio defect bc of tx. Independent of soft tissue healing, CT attachment or perio regeneration.
Biological objectives (3):
- regenerate PDL
- New cementum growth on denuded root
- New bone within defect
Clinical objectives of perio work:
- reduce/eliminate pockets
- Inc attachment
- Improve prognosis for tooth/dentition
- create potential abutment
What are the 4 types of cells that may repopulate a perio wound after surgery?
- Epithelial cells
- Cells from gingival connective tissue
- Bone cells
- Periodontal ligament (PDL) cells
What cells are the fastest to migrate?
Epithelial cells - .5mm/day. Bc the epi is so fast, it prevents CT attachment and epi will attach if there is plaque control.
In order to achieve PDL regeneration, what must be prevented?
other cells must be prevented from populating the root surface so that PDL cells can proliferate.
So, knowing that PDL cells must predominate; how is regeneration achieved?
Placing a membrane to create a space bt the root and barrier. Membrane stabilizes blood clot and permits the PDL cells to dominate the healing (by preventing downgroth of epi cells).
What is the only way o definitively prove regeneration?
histology