GTR Flashcards

1
Q

GTR requires a regeneration of what tissues to be successful?

A

cementum, PDL, alveolar bone in a previously diseased site.

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2
Q

What must you do before GTR?

A

STOP perio dz

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3
Q

Is GTR a treatment for perio dz?

A

NO - it just regenerates the defective tissue caused by perio dz

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4
Q

Define Repair:

A

wound healing by tissue that does not fully restore the architecture of the diseased part

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5
Q

Define Reattachment:

A

reunion of epithelial and CT w root surface and bone

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6
Q

Define New attachment:

A

union of CT or epi w the root that has been deprived of its original perio attachment.

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7
Q

How might something obtain new attachment?

A

epithelial adhesion, CT adaptation, or attachment and new cementum formation

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8
Q

Define bone fill:

A

reformation of all/part of bone in perio defect bc of tx. Independent of soft tissue healing, CT attachment or perio regeneration.

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9
Q

Biological objectives (3):

A
  1. regenerate PDL
  2. New cementum growth on denuded root
  3. New bone within defect
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10
Q

Clinical objectives of perio work:

A
  1. reduce/eliminate pockets
  2. Inc attachment
  3. Improve prognosis for tooth/dentition
  4. create potential abutment
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11
Q

What are the 4 types of cells that may repopulate a perio wound after surgery?

A
  1. Epithelial cells
  2. Cells from gingival connective tissue
  3. Bone cells
  4. Periodontal ligament (PDL) cells
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12
Q

What cells are the fastest to migrate?

A

Epithelial cells - .5mm/day. Bc the epi is so fast, it prevents CT attachment and epi will attach if there is plaque control.

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13
Q

In order to achieve PDL regeneration, what must be prevented?

A

other cells must be prevented from populating the root surface so that PDL cells can proliferate.

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14
Q

So, knowing that PDL cells must predominate; how is regeneration achieved?

A

Placing a membrane to create a space bt the root and barrier. Membrane stabilizes blood clot and permits the PDL cells to dominate the healing (by preventing downgroth of epi cells).

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15
Q

What is the only way o definitively prove regeneration?

A

histology

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16
Q

What is regeneration good for? (5)

A
  1. 3 wall defects or 2/3 walled combo defects
  2. CII furcations
  3. CIII furcations (~25%)
  4. Circumferential defects
  5. Recession areas
17
Q

Contraindications for regeneration? (5)

A
  1. systemic dz, endocarditis pts
  2. horizontal defects
  3. Hopeless defects
  4. compromised success due to technical error
  5. smoking ???
18
Q

What is needed for a successful regeneration case? (3)`

A
  1. patient enthusiasm
  2. successful OH phase
  3. case assessment
19
Q

7 steps for GTR

A
  1. Reflect mucoperiosteal flap
  2. preserve as much interdental papillae
  3. Excise ALL pocket epithelium
  4. Thorough debridement of root surfaces
  5. Select membrane type ( see below) and configuration most suited to defect
  6. Trim so that membrane will adapt to tooth and overlaps bone margins by 2-3mm. Suture and maintain position.
  7. Suture flap to attempt primary closure.
20
Q

Post-op after GTR?

A

OHI w/ gentle soft brush + CHX rinse + Antibiotics?? + NSAIDS ??

21
Q

When are sutures removed?

A

7-10 days

22
Q

When should non-resorbable membrane be removed?

A

6-8 weeks

23
Q

If membrane is exposed at 1 weeks review, what do you do?

A

see the patient weekly

24
Q

What to do with infection?

A

Use antibiotics

25
Q

The results will depend on what factors?

A

plaque control, surgical technique, smoking

26
Q

Examples of nonresorbable membranes?

A

Gore-Tex, ePTFE, Cytoplast

27
Q

Examples of resorbable membranes?

A

Biomend collagen; Bio-Gide porcine collagen; CpoiOs bovine pericardium; Bioexclude human amnion-chorion

28
Q

When would GTR be used with implants?

A
  1. Augment bone before implant
  2. Inc/control bone architecture at placement
  3. save failing implant
29
Q

What does emdogain do?

A

enamel matrix proteins - induces formation of new cementum, PDL, alveolar bone

30
Q

What does PRP do?

A

concentrated autogenous plasma - proveds cocktail of growth factors