GTD Flashcards
Incidence of GTN after therapeutic abrotion
1 in 20000
Classic features of Molar Pregnancy
- Irregular Vaginal Bleeding
- Hyperemesis
- Execessive Uterine Enlargement
- Early failed Pregnancy
Rarely:
- Hypothyroidism
- early onset PE
- Abd. distension d.t. theca lectin cyst
Very rare:
- Acute rep. failure
-Neuro: seizures d.t. metastasis
U/S of complete mole
5-7 w: polypoid mass
>8 w: thickened cystic appearance of the villous tissue w/o GSac
Soft markers on U/S of partial mole
Cystic Spaces in placenta
Ratio of transverse to AP dimension of Gsac is >1.5
resemble anembryonic preg. or delayed missed abortion.
Is US and clinical diagnosis confirmatory
No.
Histopathology is confirmatory
Should tissues be sent after all miscarriages to histo.
Only if the fetal tissue wasn’t identified at any stage of pregnancy.
Or if not sent, can ask her to do urine pregnancy. test after 3 weeks.
Should tissue be sent to histo after therapeutic abortion?
Not req. if fetal parts are identified & do a UPT after 3 weeks
How many cases of GTD are unrecognized prior to removal?
2.7%
TTT of choice for Complete and partial mole
Suction curetage under US guidance.
In Partial Mole if fetal parts doesn’t allow suction-> medical evacuation
Risk of developing GTN, if medical management used compared to surgical management
16 times
Risk of requiring chemo for GTN post complete mole or partial mole?
Complete: 13-16%
Partial: 0.5-1%
Can prior Cx preparation done?
Yes
Can oxytocin infusion be used prior to completion of removal
No, fear of risk of embolism.
only used in severe Haemorrhage
When is a repeat surgery indicated
If acute hemodynamic compromise d.t. persistent bleeding w/ retained products on US –> repeat surgery
repeat surgery shouldn’t be done w/o referral to GTD center.
Where are GTD centers?
LONDON
DUNDEE
SHEFFIELD