GS - Metabolic pathways Flashcards

1
Q

Which of the following best defines metabolism?

a) Balancing energy intake to maintain body weight
b) Homeostasis of blood glucose levels
c) The breakdown of food to release energy
d) The sum of anabolic and catabolic reactions within cells

A

d) The sum of anabolic and catabolic reactions within cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The primary function of cellular respiration is to generate ATP. Which of the following summarises this process?

a) Anabolism of glucose
b) Glycogenolysis
c) Oxidation of glucose
d) Reduction of glucose

A

c) Oxidation of glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Proteins, carbohydrates and fats can all be metabolised to generate a common precursor which then enters the mitochondrial matrix and citric acid cycle. What is this molecule?

a) Acetyl CoA
b) Citric acid
c) Lactic acid
d) Pyruvic acid

A

d) Pyruvic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

During exercise when oxygen is not readily available, NADH + H+ unloads its hydrogen atoms back onto pyruvic acid yielding which product?

a) Acetyl
b). Acetyl CoA
c). Lactic acid
d). Malic acid

A

c). Lactic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

The answer to the previous question is an example of what type of reaction?
a). Anabolism
b). Catabolism
c). Oxidation
d). Reduction

A

d). Reduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

At which stage of cellular respiration is CO2 generated?
a) Citric acid cycle
b) Electron transport chain
c) Glycogenesis
d) Glycolysis

A

a) Citric acid cycle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of the following most accurately describes the citric acid cycle?
a) A process which enables both catabolism and anabolism of important metabolites
b) A process which results in only the anabolism of substances
c) A process which results in only the catabolism of molecules
d) A process which takes place in anaerobic conditions

A

a) A process which enables both catabolism and anabolism of important metabolites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The electron transport chain takes place on the inner mitochondrial membrane. Direct utilisation of which molecule is exclusive to this stage of cellular respiration?
a) Carbon dioxide
b) NADH + H+
c) Oxygen
d) Water

A

c) Oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which mechanism generates the energy for creating an electrochemical gradient between the mitochondrial matrix and inner membrane?
a) Oxidation and reduction of cytochrome complexes
b) Oxidation of NADH + H+ and FADH2
c) Phosphorylation of ADP to ATP
d) Reduction of oxygen to water

A

a) Oxidation and reduction of cytochrome complexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Approximately, what is the net gain of ATP from the complete metabolism of two glucose molecules, under aerobic conditions?
a) 4
b) 30
c) 60
d) 80

A

d) 60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The formation of glucose from non-carbohydrate sources such as glycerol and amino acids in the liver, is known as?
a) Gluconeogenesis
b) Glycogenesis
c) Glycogenolysis
d) Glycolysis

A

a) Gluconeogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which component of the citric acid cycle is generated by beta oxidation of fatty acids?
a) Acetic acid
b) Acetyl CoA
c) Pyruvic acid
d) Succinyl CoA

A

b) Acetyl CoA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A person has been on a hunger strike for seven days. Compared to normal, which of the following is most likely?
a) Elevated glucose concentration in the blood
b) Increased glycogen synthase activity in the liver
c) Increased plasma insulin concentrations
d) Increased release of fatty acids from adipose tissue and ketosis

A

d) Increased release of fatty acids from adipose tissue and ketosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Transamination of amino acids results in the formation of which molecules?
a) Essential amino acids
b) Keto acids
c) Ketone bodies
d) Non-essential amino acids

A

b) Keto acids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In the absorptive state, anabolism exceeds catabolism. What is the fate of excess metabolites, regardless of source at this stage?
a) Continued cellular respiration
b) Conversion to glucose and storage as glycogen
c) Degradation in the liver and excretion in urine
d) Transformation into triglycerides

A

b) Conversion to glucose and storage as glycogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

The primary aim of the postabsorptive state is to maintain blood glucose levels between ~4 – 6 mmol/L. What is the term for release of glucose from glycogen?
a) Gluconeogenesis
b) Glycogenesis
c) Glycogenolysis
d) Glycolysis

A

c) Glycogenolysis

17
Q

Hormones are critical in monitoring absorptive and postabsorptive states. Which is classed as a hypoglycaemic hormone?
a) Cortisol
b) Glucagon
c) Insulin
d) Thyroxine

A

c) Insulin