Growth in Childhood + development Flashcards
why is growth measured?
- poor growth in infancy = associated with high childhood morbidity / mortality.
- Growth = best indicator of health
- Demonstration of normality of growth by age and stage of puberty
- Identify disorders of growth
- Assess obesity
How do you measure length of a baby?
- legs straight
- head and feed against board
What is a centile chart?
- what do they measure ?
centile chart = a way of expressing variation within the population.
- head circumference
- weight
- height/length
- leg length
- BMI
- growth velocity
- specialist charts
Height / Velocity chart is expressed in =
cm/ year
how do you calculate height velocity ?
(height now - height last visit) / (age now - age last visit)
What is the main endocrine component that controls growth?
- GH release
- causes release of IGF1
- which acts on IGF 1 receptor
- -> and triggers growth
________ axis = regulator of human linear growth
- GH-IGF-1 axis
What factors influence pulsatile secretion ?
- nutrition
- sleep
- exercise
- stress
what is the most rapid phase of growth ?
antenatal
- maternal health + placenta = important factors of growth
describe growth in infancy
- there is initial growth of approximately 23 - 25 cm in the 1st year
- there is continued growth
- nutritionally dependent
- 9-12 months influence of GH
describe growth from infancy - adolescence
- there is similar growth rate in boys + girls
- GH/IGF1 axis –> drives growth
- nutrition = less impact
NOTE:
girl - get puberty just before puberty
boys - get puberty just after / towards end of puberty
-
what stimulates pubertal growth spurt?
- sex steroids
- GH
How does a child stop growing?
- bones mature
- epiphyses fuse at end of puberty
- final growth –> occurs in spine
- final epiphyses fuse –> in pelvis
Note:
- most children settle on a centile by about 2 years (until puberty)
- pattern of growth = more important than position on centiles
-
What are the 7 causes of short stature?
- Genetic
- Pubertal and growth delay
- IUGR/SGA (intrauterine growth restriction)
- Dysmorphic syndromes (e.g down syndrome)
- Endocrine disorders (hypothyroidism, growth hormone deficiency, steroid excess)
- Chronic paediatric disease
- Psychosocial depravation