Growth Factor Families And Functions

Question 1

Epidermal growth factor (EGF)

Answer 1

Growth and proliferation of cells of ectodermal and mesodermal origin

Question 2

Transforming growth factors (TGFs)
(TGF B1 to TGF B5)
[MeMBr]

Answer 2

Formation of extracellular matrix
Epithelial branching
Myoblast(undifferentiated cell capable of giving rise to muscle cells) proliferation

[MeMBr]
M: myoblast
eM: extracellular matrix
Br: epithelial Branching

Question 3

Bone morphogenetic factors (BMP 1-9)

Answer 3

Bone formation
Cell division
Cell migration
Apoptosis

Question 4

Mullerian inhibiting factor(MIF)

Answer 4

Regression of paramesonephric duct

Question 5

Nodal

Answer 5

Formation of primitive streak

Formation of mesoderm

Question 6

Lefty

Answer 6

Determination of BODY ASSYMETRY

Question 7

Sonic hedgehog(SHH)

Answer 7

Neural tube formation

SOMITE (embryonic segmentation of the body) differentiation

Question 8

WNT proteins[pLUM]

Answer 8

Midbrain development
Urogenital differentiation
Limb patterning
[pLUM]

Question 9

Fibroblast growth factors (FGFs)

Answer 9

Mesodermal differentiation
ANGIOGENESIS
AXON GROWTH
LIMB development
BRAIN development
GENITAL TUBERCLE outgrowth

Question 10

Insulin like growth factors (IGFs)

BarFi

Answer 10

IGF 1 :BONE GROWTH
IGF 2 :FETAL GROWTH
[BarFi]

Question 11

Nerve growth factors (NGFs)[S and S]

Answer 11

Growth of sensory and sympathetic neurons

[S and S]