Groupings Flashcards
1
Q
Hand-Foot Syndrome
A
- Everolimus
- Cytarabine
- Trametinib (Mekinist) (MEK 1-2 inhibitor)
- Lapatinib (Tykerb) & Neratinib (Nerlynx)
- Sorafenib (Nexavar)
- Sunitinib (Sutent)
2
Q
QT prolongation
A
- Oxaliplatin
- Tretinoin
- Arsenic trioxide
- Droperidol (post op n/v)
- Tormefene (SERM)
- Leuprolide (Leupron Depot) (Gnrh ag)
- Goserlin (Zoladex)
- Nilotinib (Tasigna)
- Bosutinib (Bosulif)
- Dasatinib (Sprycel)
- Dabrafenib (Tafinlar) (BRAF Inhibitor)
- Vemurafenib (Zelboraf) (BRAF Inhibitor)
- Trametinib (Mekinist) (MEK 1-2 inhibitor)
- Alectinib (Alecensa) (ALK Inh)
- Brigatinib (Alunbrig) (ALK Inh)
- Ceritinib (Zykadia) (ALK Inh)
- Crizotinib (Xalkori) (ALK Inh)
- Sorafenib (Nexavar)
- Sunitinib (Sutent)
- haloperidol, thioridazine, chlorpromazine (1st g antipsy)
3
Q
Use non-PVC IV bag and tubing due to leaching of DEHP
A
- Etoposide (Topoisomerase II inhibitor)
- Carmustine (Alkylating agent)
- Temsirolimus (mTOR inhibitor)
4
Q
REMS program
A
- Revlimid, Pomalyst or Thalomid
(Immunomodulators) - Axicabtagene ciloleucel (Yescarta)
- lpilimumab (Yervoy)
- Adasuve (lozapin): bronchospasm (1st g antipsych)
- clozapine (Clozaril): Neutropenia/ agranulocytosis (2nd g antipsych)
5
Q
Intrathecal administration (fatal)
A
- Bortezomib (Velcade)
- Vinca alkaloids
6
Q
Pulmonary toxicity
A
- Busulfan
- Bleomycin
- Trastuzumab
- Brentuximab Vedotin (Adcetris)
7
Q
Serious skin reactions (SJS/TEN)
A
- Rituximab (Rituxan)
- Brentuximab Vedotin (Adcetris)
- Afatinib (Gilotrif) (EGFR I)
- Erlotinib (Tarceva) (EGFR I)
- Gefitinib (Iressa) (EGFR I)
- Sorafenib (Nexavar)
- Sunitinib (Sutent)
8
Q
Tumor lysis syndrome
A
- Rituximab (Rituxan)
- Blinatumomab (Blincyto)
9
Q
seizure risk
A
- clozapine
- bupropion
10
Q
Avoid in PKU (contains Phenylalanine)
A
- QuiliChew ER (Methylphenidate ER chewable tablet) for ADHD
11
Q
Drugs that cause hyperkalemia
A
- Unfractionated Heparin
