gritti 15 Flashcards
components of the conducting portion of the respiratory system
nasal cavities, nasopharynx, larynx, trachea, bronchii, bronchioles, terminal bronchioles
components of the respiratory portion of the respiratory system
respiratory bronchioles, alveoli, alveolar sacs and alveolar ducts
basic histological structure of an organ in the respiratory system
respiratory mucosa (supported by lamina propria)
submucosa
cartilage/muscle layer
adventitia
what is the typical epithelium of the respiratory tract?
pseudostratified ciliated columnar epithelium
main 5 cells types of the respiratory tract
-ciliated columnar cells
-goblet cells
-small granules cells (Kulchitsky cells)
-basal cells
-brush cells
bownman gland in the olfactory epithelium
a gland in the lamina propria that produces fluids around the cilia of the olfactory neurons favoring the entrance of new odorants
main cell types of olfactory epithelium
olfactory neurons
sustentacular cells
basal cells
glomeruli in the olfactory bulb
where the axons from the olfactory neurons bearing the same receptor for the same odorants are collected.
multiple glomeruli, each of them contain axons that come from olfactory neurons that bear the same receptor
Olfactory ensheathing cells
-glial cells
-are associated to olfactory neurons
-help enwrapping the axons of the olfactory neurons in fascicles and help them to arrive to the correct destination (olfactory bulb)
-in the olfactory bulb these cells helps in unwrap and re-wrap them again to facilitate the sorting to the right golumerulus
all the axons coming from the neurons expressing the same odorant receptor have to be connected to the same glomerulus in the olfactory bulb
tunica fibromusculocartilaginea.
skeleton of the trachea made of
-16-20 C shaped rings of hyaline cartilage
-trachealis muscle to fill the empty spaces on the posterior parts of the C shaped rings (smooth muscle)
-Annular ligaments (collagen+elastic connective tissue) that sorroumds the rings
which type of muscle is the trachealis?
smooth muscle
epithelium of the trachea
respiratory epithelium
columnar pseudostratified ciliated epithelium
where do we have serous mucous glands in the trachea?
in the submucosa
clara cells
start to be present from the bronchioles
secretes surfactants: a mixture of lipids that serves to lubrify and protect the mucosa
characteristics of the bronchi
-sometimes folded mucosa
-similar to trachea
-sorrounded by a layer of smooth muscle between the epithelium and the cartilage
-NOT C SHAPED CARTILAGE, BUT PIECES OF CARTILAGE->MAIN DIFFERENCE FROM THE TRACHEA
-pseudostratified ciliated columnar epithelium
bronchioles
-no cartilage
-no glands
-no goblet cells
-well developed layer of smooth muscle
-Clara cells
-the epithelium changes to simple columnar ciliated
terminal bronchioles
-simple cuboidal epithelium
-smaller
-well developed smooth muscle
-bundary between the conductive tract and the respiratory tract
respiratory bronchioles
-ciliated cuboidal/columnar epithelium
-small amount of smooth muscle
-prominent Clara cells
alveoli structure
-thin wall made of squamous epithelial cells to allow gas exchange and connective tissue
(made of reticular, collagen and elastic fibers for structure and flexibility and of macrophages and leukocytes for defense)
-alveoli are connected by alveolar pore
-inside the connective tissue there are pulmonary capillaries (where oxygen is absorbed into the blood and C02 is released)
-around the opening of each alveolus there is a layer of smooth muscle
alveolar cell types
-type I pneumocytes
flat cells connected to eachother by tight junctions
-type II pneumocytes, cuboidal shaped, contain lamellar bodies (full of surfactant components) connected to type I cells by tight junctions
-macrophages
remove particles inspired with air inspiration and get rid of excess surfactant
-capillary endothelial cells are thin but not fenestrated
Function of Surfactant
avoids the collapse of alveolar wall
blood air barrier in the alveoli is made of
-the epithelium of the alveoli made of type I pneumocytes
-fused basal lamina between type I pmneuomocytes and endothelial cells of the capillaries
-endothelium of the capillaries (thin that allows O2 to enter and C02 to go out)