Graves disease Flashcards
1
Q
What?
A
Autoimmune condition where your immune system mistakenly attacks your thyroid which causes it to become overactive.
Most common cause of hyperthyroidism
2
Q
Who?
A
> > Young or middle-aged women
Often runs in families
Smoking can also increase your risk of getting it.
3
Q
Clinical features?
A
Thyroid gland diffusely, symmetrically enlarged without nodules Bruit Graves orbitopathy/ thyroid eye disease Pretibial myxoedema Thyroid acropachy
4
Q
Thyroid eye disease?
A
Eye irritation, photophobia, excessive watering Redness of eyes, eyelids and/ or swelling Change in appearance of eye or eyelids: Eyelid retraction Lid lag Proptosis Persistent double vision Globe subluxation
5
Q
Investigations?
A
↓TSH and ↑fT4/3
6
Q
Other abnormalities?
A
Hypercalcaemia and inc ALP
Leucopenia (Dec white cells)
TRAb - raised
