Graves' disease Flashcards
1
Q
For Graves’ diseases, state:
- What it is
A
- Body produces antibodies that cause over- stimulation of the thyroid
- Patients develop antibodies against thyroid cell surface receptors for thyroid-stimulating hormone (TSH), resulting in overproduction of thyroid hormones
- Long-lasting stimulation by antibodies causes hyperthyroidism due to continuous stimulation of the thyroid gland
2
Q
For Graves’ diseases, state:
- Who is commonly affected
A
- Affects women between the age of 30 and 40
- Female to male ration is 7:1
- Familial predisposition
3
Q
For Graves’ diseases, state:
- Signs and symptoms (15)
A
- Goiter (enlarged thyroid)
- Trouble sleeping
- Irritability or nervousness
- Heat sensitivity, increased sweating
- Hand tremors
- Rapid heartbeat
- Bulging eyes
- Thinning of skin or fine, brittle hair
- Frequent bowel movements
- Weight loss without dieting
- Fatigue or muscle weakness
- Thickened red skin on shin or feet
- Tissues behind eye become inflamed and swollen
- Lighter menstrual flow and less frequent periods
- Problems getting pregnant
4
Q
For Graves’ diseases, state:
- Oral signs (9)
A
- Increased susceptibility to caries
- Increased susceptibility to periodontal disease
- Enlargement of extraglandular thyroid tissue
- Burning mouth syndrome
- Accelerated dental eruption
- Maxillary and mandibular osteoporosis
- Enamel hypoplasia
- Development of connective tissue diseases like Sjogren’s Syndrome or Systemic lupus erythematosus
- Enamel hypoplasia
