grave's disease - mx Flashcards

1
Q

Ix - result of TFTs

A
  1. high T3/T4

2. Undetectable TSH

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2
Q

Ix - which antibodies are present?

A
  1. TSH receptor antibodies (v specific)
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3
Q

Ix - choice of imagineg and what is the result?

A
  1. Iodine uptake scan

2. Shows diffuse uptake of radioactive iodine

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4
Q

Tx - first line

A

medical management :

  1. Carbimazole
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5
Q

Tx - second line

A

radioactive iodine ablation

  • second line if relapse on anti thyroid drugs
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6
Q

What is major complication of ‘Carbimazole’

A

agranulocytosis

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7
Q

When is radioiodine tx contraindicated?

A
  1. pregnancy

2. thyroid eye disease

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