grave's disease - mx Flashcards
1
Q
Ix - result of TFTs
A
- high T3/T4
2. Undetectable TSH
2
Q
Ix - which antibodies are present?
A
- TSH receptor antibodies (v specific)
3
Q
Ix - choice of imagineg and what is the result?
A
- Iodine uptake scan
2. Shows diffuse uptake of radioactive iodine
4
Q
Tx - first line
A
medical management :
- Carbimazole
5
Q
Tx - second line
A
radioactive iodine ablation
- second line if relapse on anti thyroid drugs
6
Q
What is major complication of ‘Carbimazole’
A
agranulocytosis
7
Q
When is radioiodine tx contraindicated?
A
- pregnancy
2. thyroid eye disease