Grapes/raisins - VIN

Question 1

Is grape juice toxic?

Answer 1

no known report; unknown if toxic or not

Question 2

The toxic principle is unknown? T/F

Answer 2

T

Question 3

Are grapes toxic to both dogs and cats?

Answer 3

Mainly dogs

Some cases reported in cats as per literature

Question 4

Toxic dose for grapes?

Answer 4

Unknown

toxicosis has been seen with ingestion of 0.7 oz/kg of grapes and 0.1 oz/kg of raisins

Question 5

No specific diagnostic test exists for grape toxicosis . T/F

Answer 5

T

Question 6

Do liver values increase or kidney values or both?

Answer 6

• Kidney values in most cases

- Liver values in some cases

Question 7

How soon does creatinine and BUN increase?

Answer 7

Serum creatinine begins to rise shortly after exposure, whereas BUN generally takes about 24 hours before it becomes abnormal

** generally Creatinine in 12 hr ; BUN in 24 hr

Question 8

BUN generally takes about ___hours before it becomes abnormal

Answer 8

24

Question 9

How late do you expect CS?

Answer 9

within several hours

Question 10

Vomit is seen in all reported cases. T/F

Answer 10

T

Question 11

Immediate Rx for Grape toxicity?

Answer 11

• If the ingestion is recent and dog has not already vomited, induce vomiting
• Activated charcoal can be given . For large ingestions, consider a second dose 8-12 hrs after the initial dose

Question 12

Supportive Rx for grape toxicity?

Answer 12

Rx for AKI

Question 13

Development of _______is a poor prognostic indicator

Answer 13

severe oliguria or anuria

Question 14

Can liver enzymes get high in grape toxicity?

Answer 14

Yes elevation of liver values, lipase and amylase can be seen

Question 15

Why do we say that AS LONG AS THERE IS PEE,THERE IS HOPE?

Answer 15

• If oliguric/anuric renal failure develops, then it is is poorly responsive to Rx

Usually develops within 72 hrs

Question 16

Oliguric/anuric renal failure usually develops in ____ hrs post grape/raisin toxicity

Answer 16

<72 hrs