Gram Positive Organisms Flashcards
What are the common gram positive organ types?
Staphylococci
Streptococci
Enterococci
What are the common gram positive bacilli?
Listeria monocytogenes
Clostridia
Corynebacterium
Bacillus cereus
What is another name for corynebacterium?
Aka diphtheroids.
What type of drugs do the beta-lactams include?
Penicillin Flucloxacillin Amoxicillin Cephalosporins Piperacillin/tazobactam Carbepenems
What is absorbed more orally, penicillin or amoxicillin?
Amoxicillin.
What is the mean inhibitory concentration (MIC)?
Concentration of drug required to kill 99.9% of organisms in 18 to 24 hours.
What drug class is it important to be above the MIC for as long as possible (maintain a high blood concentration)?
Beta-lactams.
What drugs have concentration dependent killing?
Aminoglycosides
Quinolones
May antibiotic penetration be site dependent?
Yes.
When may biofilms occur and do they require special thought?
CF, bronchiectasis, prosthetic material.
Yes.
What enzyme do all streptococci have?
Catalase.
Give an example of group B strep and where it causes infection?
Streptococcus agalactaiae
Pregnancy and neonates
What is the new name for strep bovis?
Streptococcus gallyllyticus subsp. gallolyticus.
What are the 2 types of enterococcus and what one is more likely to be resistant?
Enterococcus faecalis Enterococcus faecium (more resistant)
What 3 conditions does strep pneumoniae cause?
Otitis, pneumonia, meningitis
