Gram Negative Organisms

Question 1

What are the main antibiotics that may be active against gram negatives?

Answer 1

Beta-lactams 
Monobactam (aztreonam)
Aminoglycosides (gentamicin)
Macrolides
Tetracyclines
Chloramphenicol
Co-trim

Question 2

After how long in hospital can a person get a HAP?

Answer 2

48 hours.

Question 3

What antibiotic is active against haemophilus influenza?

Answer 3

Amoxicillin, doxycycline second line.

Question 4

What is the treatment for most atypical pnuemonia?

Answer 4

Doxycycline (not legionella)
Clarithromycin also works
Quinolones in penicillin allergic severe pneumonia.

Question 5

Is legionella pneumophila an intracellular or extracellular organism?

Answer 5

Intracellular.

Question 6

What is the only drug that will treat pseudomonas?

Answer 6

Ciprofloxacin

Question 7

What are some examples of coliforms?

Answer 7

E.coli
Klebsiella
Proteus
Enterobacter
Serratia

Question 8

Will cephalosporins, penicillins or aztreonam work in extended spectrum beta-lactamases?

Answer 8

No.

Question 9

How long should you prescribe gentamicin for?

Answer 9

72 hours then ID/Micro approval required

24 hours if concern about renal function