Gram-negative bacilli (rods): Escherichia coli, Enterobacter, CItrobacter, Morganella, Pseudomonas, Serratia Flashcards
Cephalosporins
Cefepime, Ceftazidime
Penicillins
Piperacillin, Ticarcillin
Monobactam
Aztreonam
Quinolones
Ciprofloxacin, Levofloxacin, Moxifloxacin, Gemifloxacin
Aminoglycosides
Gentamicin, Tobramycin, Amikacin
Carbapenems
Imipenem, Meropenem, Ertapenem, Doripenem
Exception: Ertapenem (carbapenem)
does not cover pseudomonas
Exception: Piperacillin & Ticarcillin (penicillins)
also cover streptococci and anaerobes
Exception: Levofloxacin, Gemifloxacin, and Moxifloxacin (quinolones)
are excellent pneumococcal drugs
Exception: Aminoglycosides
work synergistically with other agents to treat staph and strep
Exception: Carbapenems
are excellent antianaerobic medications. They cover Streptococci and all sensitive staphylococcus (MSSA).
Exception: Tigecycline
covers MRSA and is broadly active against gram-negative bacilli
Adverse effects: Daptomycin, Linezolid, Imipenem
Daptomycin: myopathy
Linezolid: low platelets
Imipenem: Seizures