Gram Negative Bacilli Flashcards
What color do Gram negative bacilli stain during Gram staining?
Pink/red
What is the primary cell wall component of Gram negative bacilli?
Lipopolysaccharide (LPS)
Do Gram negative bacilli have an outer membrane?
Yes
Which class of antibiotics is effective against Gram negative bacilli due to their ability to penetrate the outer membrane?
Aminoglycosides
True or False: Gram negative bacilli are often resistant to multiple antibiotics.
True
Which family of Gram negative bacilli includes Escherichia coli and Klebsiella pneumoniae?
Enterobacteriaceae
What is the shape of most Gram negative bacilli?
Rod-shaped (bacilli)
What is the primary mode of transmission for Gram negative bacilli infections?
Fecal-oral route
Which Gram negative bacillus causes whooping cough?
Bordetella pertussis
What is the most common cause of urinary tract infections (UTIs) in women?
Escherichia coli
What is the primary virulence factor of Helicobacter pylori, a Gram negative bacillus associated with peptic ulcers?
Urease
Which Gram negative bacillus causes typhoid fever?
Salmonella enterica
Which Gram negative bacillus is a common cause of nosocomial infections and is resistant to many antibiotics?
Pseudomonas aeruginosa
Which Gram negative bacillus causes bubonic plague?
Yersinia pestis
True or False: Gram negative bacilli have a thin peptidoglycan layer in their cell wall.
True
What is the shape of Neisseria gonorrhoeae, a Gram negative diplococcus?
Kidney bean-shaped
Which Gram negative bacillus causes Legionnaires’ disease?
Legionella pneumophila
What is the primary mode of treatment for infections caused by Gram negative bacilli?
Antibiotics
Which Gram negative bacillus is a common cause of food poisoning?
Salmonella enteritidis
True or False: Gram negative bacilli are typically more resistant to antibiotics than Gram positive bacteria.
True
Which Gram negative bacillus is responsible for causing Lyme disease?
Borrelia burgdorferi
What is the primary diagnostic test for identifying Gram negative bacilli?
Gram staining
Which Gram negative bacillus is a common cause of pneumonia in patients with cystic fibrosis?
Pseudomonas aeruginosa
True or False: Gram negative bacilli have a high lipid content in their cell wall.
True
Which Gram negative bacillus is responsible for causing cholera?
Vibrio cholerae
What is the primary mechanism of action of carbapenem antibiotics against Gram negative bacilli?
Inhibition of cell wall synthesis
Which Gram negative bacillus is commonly found in the normal flora of the human gastrointestinal tract?
Escherichia coli
True or False: Gram negative bacilli are often associated with hospital-acquired infections.
True
Which Gram negative bacillus is a common cause of urinary tract infections (UTIs) in sexually active women?
Escherichia coli
What is the shape of Vibrio cholerae, the causative agent of cholera?
Comma-shaped
Which Gram negative bacillus is often found in water sources and can cause a severe form of pneumonia?
Legionella pneumophila
What is the primary target of quinolone antibiotics in Gram negative bacilli?
DNA gyrase
Which Gram negative bacillus is a common cause of meningitis in newborns?
Escherichia coli
True or False: Gram negative bacilli are often associated with antibiotic resistance due to the presence of efflux pumps.
True
Which Gram negative bacillus is associated with peptic ulcers and gastric cancer?
Helicobacter pylori
