Gradual loss of vision Flashcards

1
Q

causes of gradual visual loss (8)

A
cataracts
diabetic retinopathy
glaucoma
HTN
slow retinal detachment
macular degeneration
optic atrophy
retinitis pigmentosa
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2
Q

Choroiditis definition and causes (5)

A

infection that can>granulomatous reaction caused by:

  • toxoplasmosis
  • toxocara
  • TB
  • sarcoidosis
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3
Q

presentation of choroiditis (4)

A

floating black spots
pain/redness
blurring of vision
photophobia

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4
Q

Ix in choroiditis (3)

A

CXR
Mantoux (tuberculin)
serology

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5
Q

Fundoscopy in choroiditis (4)

A

raised white-grey patch
choroidal opacities
white cells in anterior chamber
later, choroido-retinal scars form which appear as white patches and are asymptomatic unless they affect the macula

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6
Q

epidemiology, fundoscopy and complication of choroid melanomas

A

most common ocular malignancy
fundoscopy shows mottled grey/black patch
there is retinal detachment over the melanoma

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7
Q

Rx of choroid melanomas (5)

A
enucleation
plaque/local radiotherapy
photocoagulation
trans-pupillary thermotherapy
micro-surgical resection
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8
Q

RFs for age-related macular degeneration (7)

A
hypermetropia
female
caucasian
blue eyes
low B12
high cumulative light exposure
genesd
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9
Q

Features of macula in ARMD (5)

A
pigment
drusen-fatty deposits
optic disc is irregular, lumpy and yellow
absent optic cup
sometimes there is bleeding
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10
Q

Features of dry(non-neovascular) ARMD (3)

A

90% of ARMD
mainly drusen and degenerative changes at macula
slow progression

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11
Q

Fundoscopy of wet ARMD (3)

A

retinal pigment epithelium thickens
drusen develops
new choroidal vessels grow from choroid>neurosensory retina and cause leakage of blood.

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12
Q

key clinical features of wet ARMD (2)

A

rapid deterioration of CENTRAL vision-may only take a few wks.

distorted vision

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13
Q

Ix or wet ARMD (2)

A

fundoscopy shows fluid exudation and localised detachment of pigment

fluorescin angiography allows visualisation of the extent of neovascularisation

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14
Q

Rx of wet ARMD

A

regular monitoring w. fluorescin angiography
intravitreal anti-VEGF: bevacizumab/ranalizumab
photocoagulation
intravitreal steroids as an adjunct-triamcinolone

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15
Q

Other measures in wet ARMD (3)

A

screening once signs have been identified e.g. Amsler grid
visual aids
diet:leafy green vegetables, omega 3, zinc, vit B+C+E, beta carotene(avoid in smokers), lutein

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16
Q

Presentation, aetiology, fundoscopy and Rx of Stargardt macular degeneration (4)

A

gradual visual loss in teenagers
assoc. w. many genetic mutations.
fundoscopy shows prominent yellow flecks
Rx w. embyronic stem cells

17
Q

Pathogenesis and features of tobacco-alcohol amblyopia (4)

A

cyanide radicals from combined smoking and alcohol excess lead to optical atrophy, loss of red-green discrimination and scotoma.

18
Q

Categories of cataracts (5)

A

immature-red reflex still present
dense-no red reflex+unable to visualise fundus
nuclear sclerotic-change in refractive index w. age
anterior/posterior polar cataracts-localised, commonly inherited and lie in visual axis
subcapsular opacities (e.g. from steroids) are just deep to the lens capsule

19
Q

RFs for cataracts (13)

A
age/UV exposure
hypocalcaemia
turner's
galactosaemia
steroid use
infection-congenital rubella
dystrophia myotonica (cataracts, male pattern baldness, heart block and locking muscles)
DM
chronic anterior uveitis
down's
irradation
touching lens during surgery
high myopia
20
Q

Presentation of cataracts (5)

A
blurred vision
frequent change in specs prescription
dazzle
monocular diplopia
vision may improve w. pinholing
21
Q

fundoscopy and important Ix at Dx of cataracts

A

black dot in middle of red reflex>cataract obscuring path of light to the retina

do fasting blood glucose at Dx

22
Q

surgical Mx of catarcts including pre and post-op (6)

A

pre: ocular biometry to measure curvature of cornea and length of eye

during:

  • phacoemulsion: break down and aspirate lens
  • insert prosthetic lens

post:

  • may have Sx of imbalance
  • lens can’t accomodate => new reading glasses needed
  • anti-inflammatory eye drops and Abx needed for 4-6wks
23
Q

complications of cataracts surgery (6)

A
lens thickening
irritation
astigmatism becomes more noticeable
anterior uveitis 
intra-ocular lens dislocation
rarely:vitreous haemorrhage, glaucoma and endopthalmitis
24
Q

Features of intra-ocular lens dislocation (6)

A
decreased vision
diplopia
halos in vision
streaks of light in vision
lens glare
photosensitivity
25
Causes of intra-ocular lens dislocation (5)
``` Marfan's (upwards) EDS trauma uveal tumours homocysteinuria (downwards) ```
26
Mx of cataracts at birth and complications
correct by 6wks during latent visual period otherwise risk deprivation amblyopia (lazy optic nerve)
27
pathogenesis of glaucoma (2)
raised IOP>optic neuropathy | death of retinal ganglion cells and their nerve axons
28
Definition of glaucoma (2)
visual field defects in =/>3 areas cup:disc ratio>0.5 (raised IOP not part of criteria)
29
pattern of visual loss in glaucoma (2)
nasal and superior fields lost first | temporal field lost last
30
high risk groups for glaucoma (4)
>35yrs w. +ve 1st degree FHx Afro Caribbean myopia DM/thyroid eye disease
31
Screening tests for glaucoma (3)
multiple stimulus static visual field testing documenting optic cupping measuring IOP via tonometry (10-20 normal) (raised IOP warrants annual screening)
32
Rx of glaucoma (6)
prostaglandin analogues 1st line: latanoprost, travoprost (increased uveoscleral outflow) beta-blockers 2nd line: timolol, betaxol (decreased aqueous production) alpha adrenergic agonists: brimonidine, apraclonidine (increased outflow+decreased production) carbonic anhydrase inhibitors: acetazolamide, dorzolamide, brinzolamide (decreased production) Miotics: pilocarpine (decreased resistance to outflow) sympathomimetics: dipivefrine surgery: trabeculectomy for refractory cases
33
definition and fundoscopy of optic atrophy (2)
death of retinal ganglionic cells which make up optic nerve | fundoscopy shows brighter, well-demarcated optic disc
34
Causes of optic atrophy (6)
raised IOP: glaucoma inflammation: optic neuritis, syphilis external pressure: intra-orbital tumours, Paget's affecting skull ischaemia: centra retinal artery occlusion hereditary: leber's optic atrophy, freidrich's ataxia retinal damage: choroiditis, cerebrolmacular degeneration, retinitis pigmentosa