GP Pharmacology Flashcards

1
Q

Acetylcysteine - system and indication

A

GI system and nutrition, poisoning
Contrast nephropathy, overdose, poisoning, respiratory secretions

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2
Q

Activated Charcoal - system and indications

A

Poisoning
Overdose

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3
Q

Adenosine - System and indications

A

Cardiovascular
Supraventricular tachycardia

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4
Q

Adrenaline - system and indication

A

Cardiovascular
Anaphylaxis, cardiac arrest, local anaesthesia, mucosal bleeding, ventricular fibrillation/tachycardia

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5
Q

Aldosterone Antagonists - system, examples and indications

A

Cardiovascular
Spironolactone, Epleronone
Ascites, HF, Hyperaldosteronism

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6
Q

Alginates/Antacids - system, example and indications

A

Gi system and nutirition
Gaviscon, Peptac
Dyspepsia, GORD

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7
Q

Allopurinol - system and indications

A

Musculoskeletal system
Chemotherapy (tumour lysis syndrome), Gout

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8
Q

Alpha-Blockers - system, examples and indications

A

Cardiovascular, renal and GU
Doxazosin, Tamsulosin
Benign Prostatic Hyperplasia, Hypertension

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9
Q

Aminoglycosides - system, examples and indications

A

Infection
Gentamicin, Amikacin
Endocarditis, Pyelonephritis, Sepsis

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10
Q

Aminosalycilates - system, examples and indications

A

GI system and nutrition, Muscuoloskeletal system
Mesalazing, Sulfasalazine
Rheumatoid Arthritis, Ulcerative Colitis

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11
Q

Amiodarone - system and indications

A

Cardiovascular
Atrial Fibrillation/Flutter, Cardiac Arrest, Supraventricular tachycardia, Ventricular fibrillation/tachycardia

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12
Q

Angiotensin Converting Enzyme Inhibitors - system, examples and indications

A

Cardiovascular
Ramipril, Lisinopril, Perindopril
Acute Coronary Syndrome, Chronic Kidney Disease, Diabetic neuphropathy, HF, Hypertension, Ischaemic Heart Disease

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13
Q

Angiotensin Receptor Blockers - system, examples and indications

A

Cardiovascular
Candesartan, Losartan, Irbesartan
CKD, Diabetic neuropathy, HF, HTN, IHD

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14
Q

Antidepressents: Selective Serotonin Reuptake Inhibitors - system, examples and indications

A

Nervous System
Fluoxetine, Citalopram, Sertraline
Anxiety, Depression, OCD

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15
Q

Antidepressants: Tricyclics and related drugs - system, examples and indications

A

Nervous System
Amitriptilline, Lofepramine
Depression, Neuropathic pain

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16
Q

Antidepressants: Venlafaxine and Mirtazapine - system and indications

A

Nervous System
Anxiety, Depression

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17
Q

Antiemetics: Dopamine D2 Receptor Antagonists - system, examples and indications

A

Nervous System, GI system and nutrition
Metoclopramide, Domperidone
Nausea and Vomiting

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18
Q

Antiemetics: Histamine H1 Receptor antagonists - system, examples and indications

A

Nervous System, GI system and nutrition
Cyclizine, Cinnarizine, Promethazine
Anaphylaxis, Nausea and Vomiting

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19
Q

Antiemetics: Phenothiazines - system, examples and indications

A

Nervous System, GI system and nutrition
Prochlorperazine, Chlorpromazine
Agitation, Psychomotor symptoms, N&V

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20
Q

Antiemetics: Serotonin 5-HT2 Receptor Antagonists - system, examples and indications

A

Nervous System, GI system and nutrition
Ondansetron, Granisetron
Chemotherapy, N&V. Panic disorders

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21
Q

Antifungal drugs - system, examples and indications

A

Infecition
Miconazole, Fluconazole, Clotrimazole, Nystatin
Fungal Infections

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22
Q

Antihistamines: H1 Receptor Antagonists - system, examples and indications

A

Respiratory
Chlorphenamine, Cetirizine, Loratadine, Fexofenadine
Allergy, Hayfever, Pruritus, Urticaria

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23
Q

Antimotility drugs - system, examples and indication

A

GI system
Loperamide, Codeine phosphate
Diarrhoea

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24
Q

Antimuscarinics: Bronchodilators - system, examples and indications

A

Respiratory
Ipratropium Bromide, Tiotropium
Asthma, COPD

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25
Q

Antimuscarinics: Cardiovascular and GI uses - examples and indications

A

Atropine, Hyoscine Butylbromide, Glycopyrronium
Bradycardia, IBS, Respiratory secretions

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26
Q

Antimuscarinics: GU uses - examples and indication

A

Oxybutinin, Tolterodine, Solifenacin
Urinary incontinence

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27
Q

Anti-psychotics first generation (typical) - system, examples and indications

A

Nervous System
Haloperidol, Chlorpromazine, Prochlorperazine
Agitation, Bipolar Disorder, N&V, Schizophrenia

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28
Q

Anti-psychotics second generation (atypical) - system examples and indications

A

Nervous System
Quetiapine, Olanzapine, Risperidone, Clozapine
Agitation, Bipolar Disorder, Schizophrenia

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29
Q

Aspirin - system and indications

A

Cardiovascular, Nervous System
Acute Coronary Syndrome, AF, Fever, IHD, Pain, Peripheral arterial disease, Stroke

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30
Q

Benzodiazepines - system, examples and indications

A

Nervous system, poisoning
Diazepam, Midazolam, Temazepam, Lorazepam, Chlordiazepoxide
Alcohol Withdrawal, Anxiety, Status Epilepticus, Insomnia, Poisoning, Sedation

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31
Q

Beta2 agonists - system, examples and indications

A

Respiratory
Salbutamol, Sameterol, Terbutaline
Asthma, COPD, Hyperkalaemia

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32
Q

Beta-blockers - system, examples and indications

A

Cardiovascular
Bisoprolol, Atenolol, Propranolol, Metoprolol
Acute Coronary Syndrome, Angina, AF, HF, HTN, IHD, Supraventricular tachycardia

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33
Q

Bisphosphonates - systems, examples and indications

A

Endocrine and Reproductive
Alendronic acid (alendronate), Risedronate, Disodium Pamidronate, Zolendronic Acid
Bone metastases, Hypercalcaemia of malignancy, Osteoporosis, Pagets disease

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34
Q

Calcium and Vitamin D - systems, examples and indications

A

GI system and nutrition, Renal and GU, MSK
Adcal-D3, Colecalciferol, Calcium Carbonate, Calcium Gluconate, Alfacalcidol
CKD, Hyperkalaemia, Hypocalcaemia, Osteoporosis, Vit D deficiency

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35
Q

Calcium Channel Blockers - system, examples and indications

A

Cardiovascular
Amlodipine, Verapamil, Nifedipine, Diltiazem
Angina, AF, HTN, Supraventricular tachycardia

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36
Q

Carbamazepine - system and indications

A

Nervous System
Bipolar Disorder, Epilepsy focal, Trigeminal Neuralgia

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37
Q

Cephalosporins and Carbapenems - system, examples and indications

A

Infection
Cefalexin, Cefotaxime, Meropenem
Infection (complex), Meningitis, Pneumonia, Sepsis, UTI

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38
Q

Clopidogrel - system and indications

A

Cardiovascular
Acute Coronary Syndrome, AF, IHD, Peripheral Arterial Disease, Stroke

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39
Q

Compound Inhalers (B2-agonist + costicosteroid) - system, examples and indications

A

Respiratory
Seretide, Symicort
Asthma, COPD, Inflammation

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40
Q

Corticosteroids (glucocorticoids) Inhaled - system, examples and indications

A

Respiratory
Beclomethasone, Fluticasone, Budesonide
Asthma, COPD, Inflammation

41
Q

Corticosteroids (glucocorticoids) systemic - system, examples and indications

A

Endocrine and Reproductive
Prednisolone, Hydrocortisone, Dexamethasone
Addisons Disease, Adrenal Insufficiency, Allergy, Anaphylaxis, AF, Chemotherapy, Hypopituitarism, Inflammation

42
Q

Corticosteroids (glucocorticoids) topical - system, examples and indication

A

Skin
Hydrocortisone, Beclomethasone
Eczema

43
Q

Digoxin - system and indications

A

Cardiovascular
AF, HF

44
Q

Dipyridamole - system and indications

A

Cardiovascular
Myocardial Perfusion
Scan
Stroke

45
Q

Diuretics: Loop - system, examples and indications

A

Cardiovascular, Renal and GU
Furosemide, Bumetanide
Ascites, Breathlessness, HF, Oedema

46
Q

Diuretics: Potassium Sparing - system, example and indication

A

Cardiovascular, Renal and GU
Amiloride
Hypokalaemia

47
Q

Diuretics: Thiazide (like) - system, examples and indications

A

Cardoivascular, Renal and GU
Bendroflumethiazide, Indapamide
Hypertension

48
Q

Dopaminergic drugs for Parkinsons Disease - system and examples

A

Nervous System
Levodopa (as co-beneldopa or co-careldopa), Ropinirole, Pramipexole

49
Q

Emollients - system, examples and indications

A

Skin
E45, Zerobase, Liquid Paaraffin
Dry Skin, Eczema, Psoriasis

50
Q

Fibrinolytic Drugs - system, examples and indications

A

Cardiovascular
Alteplase, Reteplase
Acute Coronary Syndrome, IHD, Pulmonary Embolism, Stroke, Venous thromboembolism

51
Q

Gabapentin and Pregabalin - system and indications

A

Nervous System
Anxiety, Epilepsy focal, Migraine, Neuropathic pain

52
Q

H2- receptor antagonists - system, example and indications

A

GI system and nutrition
Ranitidine
Dyspepsia, GORD, Peptic Ulcer Disease

53
Q

Heparines and Fondaparinux - systems, examples and indications

A

Cardiovascular, Blood
Enoxaparin, Dalteparin, Fondaparinux, Unfractionated heparin
Acute Coronary Syndrome, DVT, PE, Venous thromboembolism prophylaxis and treatment

54
Q

Insulin - system and indications

A

Endocrine
DM, Diabetic ketoacidosis, Hyperglycaemic hyperosmolar syndrome, Hyperkalaemia

55
Q

Iron - system, examples and indication

A

GI, Blood
Ferrous Fumarate, Ferrous Sulfate
Anaemia

56
Q

Laxatives: bluk forming - system, example and indications

A

GI
Ispaghula husk methylcellulose
Constipation, Diarrhoea, Faecal impaction

57
Q

Laxatives: stimulant - system, examples and indications

A

GI
Senna, Bisacodyl, Glycerol suppositories, Docusate sodium
Constipation, Faecal impaction

58
Q

Laxatives: osmotic - system, examples and indications

A

GI
Lactulose, Macrogol, Phosphate enema
Bowel preparation, Constipation, Faecal Impaction, Hepatic encephalopathy

59
Q

Lidocaine (with or without adrenaline) - system and indication

A

Cardiovascular, Nervous System
Local Anaesthesia

60
Q

Macrolides - system, examples and indications

A

Infection
Clarithromycin, Erythromycin, Azithromycin
H-Pylori eradication, Pneumonia, Skin and soft tissue infection

61
Q

Metformin - system and indication

A

Endocrine and Reproductive
DM

62
Q

Methotrexate - system and indications

A

MSK
Chemotherapy, Psoriasis, Rheumatoid Arthritis

63
Q

Metronidazole - system and indications

A

Infection
Clostridium Difficile, Colitis, Dental Infection, Protozoal Infections, Pneumonia, Intra-abdominal sepsis

64
Q

Naloxone - system and indications

A

Nervous System, Poisoning
Opioid Toxicity, Poisoning

65
Q

Nicorandil - system and indication

A

Cardiovascular
Angina

66
Q

Nicotine Replacement and related drugs - examples and indication

A

Nicotine as various brands, Bupropion, Varenicline
Smoking cessation

67
Q

Nitrates - system, examples and indications

A

Cardiovascular
Isosorbide Mononitrate
Glyceryl Trinitrate
Acute Coronary Syndrome, Angine, Pulmonary oedema

68
Q

Nitrofurantoin - system and indication

A

Infection
UTI

69
Q

Non-Steroidal Anti-Inflammatory Drugs - System, examples and indications

A

MSK
Ibuprofen, Naproxen, Etoricoxib
Gout, Inflammation, Pain

70
Q

Ocular Lubricants - system, examples and indications

A

Opthalmology
Carbomer, Hypromellose
Dry eyes, Keratoconjunctivitis sicca, Sjogrens syndrome

71
Q

Oestrogens and Progestrogens - systems, examples and indications

A

Renal and GU, Endocrine and Reproductive
Compined Pill products, Desogestrel, Oestrogen only and combined HRT
Hormonal Contraception
Hormone replacement therapy

72
Q

Opioids, Compound preparations - system, examples and indication

A

Nervous System
Co-codamol, Co-dydramol
Pain

73
Q

Opioids, strong - system, examples and indications

A

Cardiovascular, Nervous System
Morphine, Oxycodone, Fentanyl
Acute Coronary Syndrome, Breathlessness, Pain, Pulmonary oedema

74
Q

Opioids, weak - system, examples and indication

A

Nervous System
Codeine, Dihydrocodeine, Tramadol
Pain

75
Q

Oxygen - system and indications

A

Respiratory, Poisoning
Carbon Monoxide Poisoning, Hypoxaemia, Pneumothorax, Poisoning

76
Q

Paracetamol - system and indications

A

Nervous System
Pain, Fever

77
Q

Penicillins - system, examples and indications

A

Infection
Benzylpenicillin, Phenoxymethylpenicillin
Endocarditis, Meningitis, Pneumonia, Spesis, Skin and soft tissue infection, Tetanus, Tonsillitis

78
Q

Penicillins, anti-pseudomonal - system, examples and indications

A

Infection
Piperacillin with tazobactam
Infections (complex), Pneumonia, Sepsis (incl intra-abdominal), Skin and soft tissue infection, UTI

79
Q

Penicillins, broad spectrum - system, examples and indications

A

Infection
Amoxicillin, Co-amoxiclav
H-Pylori eradication, Pneumonia, Intra-abdominal sepsis, UTI

80
Q

Penicillins, Penicillinase resistant - system, example and indications

A

Infection
Flucloxacillin
Endocarditis, Osteomyelitis, Septic Arthritis, Skin and soft tissue infection

81
Q

Phenytoin - system and indications

A

Nervous System
Epilepsy (focal), epilepsy (generalised), status epilepticus

82
Q

Phosphodiesterase (type 5) inhibitors - system, examples and indications

A

Respiratory, renal and GU
Sildenafil, Tadalafil
Eractile Dysfunction, Pulmonary hypertension

83
Q

Proton Pump Inhibitors - system, examples and indications

A

GI and nutrition
Omeprazole, Lansoprazole
Dyspepsia, GORD, H-Pylori eradication

84
Q

Quinine - system, example and indications

A

MSK, Infection
Quinine Sulfate
Leg cramps, malaria

85
Q

Quinolones - system, examples and indications

A

Infection
Ciprofloxacin, Levofloxacin
Pneumonia, UTI

86
Q

Statins - system, examples and indications

A

Cardiovascular
Atrovastatin, Simvastatin, Pravastatin
Acute Coronary Syndrome, Hyperlipidaemia, IHD

87
Q

Sulphonylureas - system, example and indication

A

Endocrine
Cliclazide
DM

88
Q

Tetracyclines - system, examples and indications

A

Infection
Oxytetracycline, Doxycycline, Lymecycline
Acne, Lyme disease, Pneumonia

89
Q

Thiazolidinediones - system, example and indication

A

Endocrine
Pioglitazone
DM

90
Q

Thyroid Hormones - system, example and indications

A

Endocrine
Levothyroxine
Hypopituitarism, Hypothyroidism

91
Q

Trimethoprim - system and indications

A

Infection
Pneumocystis, Pneumonia, UTI

92
Q

Valproate - system, examples and indications

A

Nervous System
Sodium Balproate, Valproic Acid
Bipolar Disorder, Epilepsy (absence), Epilepsy (focal), Epilepsy (Generalised)

93
Q

Vancomycin - system and indications

A

Infection
Clostridium Difficile, Colitis, Endocarditis, Osteomyelitis, Sepsis

94
Q

Vitamins - systems, examples and indications

A

Nervous System, GI and nutrition, Blood, Poisoning
Folic acid, Thiamine, Hydroxycobalamin, Phytomenadione
Anaemia, Korsakoffs psychosis, Prevention of neural tube defects, Poisoning, Subacute combined degeneration of the cord, Thiamine Deficiency, Vitamin K deficiency/reversal of warfarin, Wernickes encephalopathy

95
Q

Warfarin/NOACs - systems, examples and indications

A

Cardiovascular, Blood
Warfarin, Rivaroxaban, Apixaban
DVT, Heart Valve Replacement, Pulmonary embolism, Venous thromboembolism treatment

96
Q

Z- drugs - system, examples and indication

A

Nervous System
Zopiclone, Zolpidem
Insomnia

97
Q

5a-reducatase inhibitors - system, example and indication

A

Renal and GU
Finasteride
Benign Prostatic Hypertrophy

98
Q
A