GP Flashcards
What is polypharmacy?
The concurrent use of multiple medications by one patient
What is concordance?
The agreement reached after negotiation between a patient and doctor that respects the beliefs and wishes of the patient in determining whether, when and how medicines are taken
Why might a patient struggle to stick to medication?
- Lack of motivation
- Lack of understanding of drug
- Fear of side effects
- Misconceptions about drug
- Language barrier
Benefits of breastfeeding for the baby
- Immunity
- Reduces risk of infection
- Reduces risk of SIDS
- Reduces risk of obesity and CVD
- Reduces risk of diarrhoea and vomiting
Benefits of breast feeding for the mother
- Creates bond with baby
- Reduces risk of breast cancer and ovarian cancer
- Reduces risk of osteoporosis
- Reduces risk of CVD and obesity
Complications after vaginal delivery
- CVD
- Infection or sepsis
- Hemmhoragic stroke
- Thrombotic pulmonary embolism
- Hypertensive disorders of pregnancy
- Anaesthesia problems
- Post natal depression (10-20%)
- Perineal scarring
- Back pain
How to check brain damage in a baby after ventouse suction delivery
- Examine motor movements
- Hydrocephalis measurements
What would class as an abnormal growth chart result?
- Lower than the 2nd percentile
- Higher than the 98th percentile
- Not consistent (deviation of 2 centiles is worrying)
Red reaction test
- Done at birth to check for retinoblastoma
- For adults, its used to test for cataracts
- Looking for red reflection of the retina
Which vaccines are given under 1 years old?
- 6-in-1
- Rotavirus
- MenB
- Pneumococcal
Which vaccines are given age 1-15?
- MenB
- Hib/MenC
- MMR
- Pneumococcal
- Flu vaccine every year (2-10)
- 4-in-1 preschool booster
- 3-in-1 teenage booster
- HPV
- MenACWY
What vaccines are included in the 6-in-1?
- Diphtheria
- Hepatitis B
- Hib
- Polio
- Tetanus
- Pertussis (whooping cough)
What vaccines are included in the 4-in-1?
- Diphtheria
- Tetanus
- Pertussis (whooping cough)
- Polio
What vaccines are included in the 3-in-1?
- Tetanus
- Diphtheria
- Polio
Vaccines given to adults
- 50+ years - Flu
- 65 years - Pneumococcal
- 70 years - Shingles
Vaccines given to pregnant women
- During flu season - flu from 16 weeks pregnant
- Pertussis
What condition should you be worried about if a newborn’s growth is abnormally fast?
Gigantism
What condition should you be worried about if a newborn’s growth is abnormally slow?
Hypothyroidism
What is the most common cause of a heart murmur in a baby in the first 24 hours which goes within 3 days?
Patent ductus arteriosis - lasts for about 5 days. 1/3 close spontaneously, if it is significant, it can lead to heart failure.
What would splenomegaly in newborns be a sign of?
Haemolytic disease of the newborn
Sign of hypothyroidism in a baby
A large anterior fontanelle and anything more than a fingertip breadth posterior fontanelle
What are some major risk factors for postnatal depression?
- History of mental health problems
- Psychological disturbance during pregnancy
- Poor social support
- Poor relationship with partner
- Recent major life event
- Baby blues
What is the recommended treatment for mild to moderate post natal depression?
Facilitated self-help strategies
What is the recommended treatment for mild post natal depression with a history of severe depression?
Antidepressant
What is the recommended treatment for moderate to severe post natal depression?
- CBT
- Antidepressant treatment
What are some complications children can face due to postnatal depression in their parent?
- Marked changes in behaviour
- Cognitive impairment
- Insecurity in forming attachments
- Early onset depression
- Negative effects in Language skills and IQ
Baby checks
- First 72 hours of life - heel prick test (CF, sickle cell, congenital hypothyroid)
- 6-8 weeks - check arms, eyes, heart, hips
General routes of administering paracetamol
- Oral (PO)
- Rectal (PR)
- Intravenous (IV)
- Intramuscular (IM)
- Subcutaenous (SC)
- Topical (TOP)
- Intranasal (IN)
- Sublingual (SL)
- Nebulised (NEB)
- Inhaled (INH)
How can paracetamol be given to a patient of any age (including neonates)?
- PO via tablet, capsule, suspension tablet or effervescent tablet
- PR via suppository
- IV via solution or infusion
Describe the 3 stages of lochia
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What percentage of people have at least one further depressive episode after their initial episode?
80%
Most common barriers for receiving effective care for a mental health condition
- Lack of resources
- Lack of trained healthcare providers
- Social stigma of mental disorderer
How many people who experience a major depressive episode recover within 6 months?
50%
How many people who experience a major depressive episode recover within a year?
75%
Why can depression cause fatigue?
- It affects neurotransmitters in the brain that control awakeness
- It disrupts sleeping patterns
- The stress the patient is dealing with doesn’t allow them to sleep
Mortality rate for major depressive disorder
About 10%
Common differential diagnoses for ‘feeling tired all the time’
- Hypothyroidism
- Anemia
- Anxiety disorder
- Depression
- Cancer
- CFS
- Diabetes
- Chronic kidney disease
- Fibromyalgia
- COVID …and more
Classes of antidepressants
- Selective serotonin reuptake inhibitors
- Selective noradrenaline reuptake inhibitors
- Tricyclic antidepressants
- Tetracyclic anti depressants, eg: mirtazapine
- Monoamine oxidase inhibitors (inihibit reuptake of serotonin, dopamine and noradrenaline), eg: selegeline
- Serotonin receptor and reuptake inhibitors, eg: trazodone
What non pharmacological treatment for depression has the highest strength of evidence?
CBT
In CBT, what 5 main areas are problems broken down into?
- Situations
- Thoughts
- Emotions
- Physical feelings
- Actions
Exceptional circumstances that mean antidepressants can be prescribed in mild depression
- Past medical History of moderate to severe depression
- Mild depression that has been present for two years
- Continued presence of Mild depression after other interventions
How long does it usually take for antidepressants to provide benefit?
3-6 weeks
Potential side effects of antidepressants
- Sexual dysfunction
- Weight gain
- Hyponatraemia
- Agitation
- Risk of self harm
- Serotonin syndrome
Cycle of change
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When does diabetic ketoacidosis occur?
More common in T1DM but can occur at severe stages of T2DM/T1.5
What is diabetic ketoacidosis characterised by?
Need all 3 of the following to be diagnosed:
1. Hyperglycaemia
2. Metabolic acidosis
3. Ketonaemia
What is the leading cause of death for people with T2DM?
- Macrovascular issues
- Atherosclerotic CVD
- Stroke
- Peripheral arterial disease
Diabetic kidney disease can be caused by and is first identified by:
Caused by:
1. Diabetic neuropathy
2. Hypertension
3. Renal atheroma or ischaemia
First sign:
1. Proteinuria
Diabetes is the most common cause of CKD and end stage renal disease
Risk of diabetic vision problems
- 2x increased risk of cataracts
- 1.5x increased risk of glaucoma
- Diabetes is the leading cause of prevetable sight loss in the UK
Diabetic peripheral neuropathy epidemiology and presentation
- Estimated to affect up to 50% of people with diabetes
- Common presentation: Distal and symmetrical polyneuropathy
Risk of depression in people with diabetes
2x increase
What should be tested in a diabetic annual review?
- BMI
- BP
- HbA1c
- Cholesterol
- Smoking status
- Foot examination
- Albumin:Creatinine ratio
- Serum Creatinine measurement
Examples of primary diabetes prevention
- Exercise
- Dietary modification
- Smoking cessation
Examples of secondary diabetes prevention
- Home blood glucose monitoring
- Routine annual diabetic review
Example of tertiary diabetes prevention
Screening for diabetic retinopathy and other complications
Key symptoms of diabetic retinopathy
- Seeing floaters
- Blurred or patchy vision
- Eye pain or redness
- Difficulty seeing in the dark
- Worsening vision/sudden vision loss