Gout and Nocturnal Leg Cramps Flashcards
What can cause Hyperuricaemia and Gout
- high salt diet
- Bendroflumethazide
- Chemotherapy Drugs
How to treat acute Gout attack
- Colchicine 500mg TDS
or - High dose NSAID + PPI
or - Short course of corticosteroids
Which NSAID can not be used in acute Gout treatment
Aspirin
Dose spacing of Colchicine for acute Gout
do not repeat course within 3 days
What should you not give with diuretic in Gout treatment and why
NSAID
as both medications cause fluid retention
What is chronic Gout categorised as
2 or more Gout attacks on one year
What is the 1st and 2nd Line for Chronic Gout
1st Line:
Allopurinol
2nd Line:
Febuxostat
What type of drug is Allopurinol
Xanthine-oxidase Inhibitor
What happens if acute Gout attacks happen during chronic treatment
Treat with normal acute Gout treatment
What is the side effect of Allopurinol and what should you
Rash
Discontinue, restart when it goes
–> if rash reoccurs STOP
Allopurinol Interactions
Azathioprine and Mercaptopurine
(if using with Allopurinol, reduce their dose by 1/2)
How to treat Nocturnal leg cramps
Quinine Sulphate
When should you use Quinine Sulphate for nocturnal leg cramps
if nocturnal leg cramps regularly…
- affects sleep
- painful
- non-drug doesn’t work
How long should you trial Nocturnal Leg Cramps treatment for
4 weeks
When should you asses if Nocturnal Leg Cramp treatment is needed
3 months then review
