GOSH Flashcards

1
Q

Early medical abortion

A

less than 63 days (<9 WEEKS)

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2
Q

Late medical abortion

A

9-24 weeks

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3
Q

Medical method of early abortion <9 weeks

A

200mg of oral mifepristone - wait 24-48 hours – 400mg oral misoprostol

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4
Q

Medical method of early abortion 7-9 weeks

A

200mg of oral mifepristone – wait 24-48 hours- 800mg misoprostol given vaginally buccal or sublingual route.

If abortion hasn’t occurred within 4 hours of misoprostol, give a second dose of misoprostol 400mg vaginally or orally

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5
Q

Late medical abortion 9-13 weeks

A

200mg of oral mifepristone – wait 36-48 hours- give 800mg of misoprostol vaginally.

Max of 4 more doses of misoprostol 400mg can be given at 3 hourly rates.

If abortion doesn’t occur, mifepristone can be repeated 3 hours after last dose of misoprostol and then 12 hours after this dose of mifepristone, misoprostol may be recommended again
(so mifepristone- wait 36-48 hours- misoprostol- misoprostol (option 4x misoprostone)- no abortion-mifepristone- misoprostol)

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6
Q

Late medical abortion 13-24 weeks

A

200mg of oral mifepristone- wait 36-48 hours- give 800mg misoprostol vaginally, THEN misoprostol 400mg oral or vaginally 3 hourly (to a max of 4 doses)

If abortion doesn’t occur, mifepristone can be repeated 3 hours after last dose of misoprostol and then 12 hours after this dose of mifepristone, misoprostol may be recommended again
(so mifepristone- wait 36-48 hours- misoprostol- misoprostol (option 4x misoprostone)- no abortion-mifepristone- misoprostol)

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7
Q

Pain relief in abortions?

A

NSAIDS (not paracetamol!)

Some women may require additional narcotic analgesia, particularly after 13 weeks of gestation.

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8
Q

Risks unique to medical abortion compared to surgical abortion

A
  • Unpredictable time to complete the procedure (variable)
  • Side effects of drugs such as nausea, vomiting, diarrhoea, headache, dizziness, fever/chills (common)
  • Undiagnosed ectopic pregnancy (1 in 7,000) for early medical abortion <10weeks
  • Rupture of the uterus/womb (1 in 1000) for late medical abortion >10weeks
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9
Q

Surgical abortion up to 14 weeks?

A

Vacuum aspiration

  • Cervical prep up to 14 weeks: Misoprostol 400mg vaginally 3 hours prior to sugery OR 2-3 hours sublingual prior to surgery (can be done by women or clinician)
  • Access to ultrasound during vacuum aspiration is recommended but not routinely required for uncomplicated procedures
  • Vacuum aspiration may be performed from 14 to 16 weeks of gestation using large-bore cannulae and suction tubing
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10
Q

Surgical abortion between 15-24 weeks?

A

Dilation and evacuation.

Need Cervical preparation after 14 weeks

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11
Q

Risks unique to SURGICAL ABORTION that arent in Medical abortion

A
  • Injury to the cervix (1 in 11,000) for VA, 1 in 5,000 for D&E)
  • Perforation of the uterus/womb (1 in 6,500 for VA, 1 in 2,500 for D&E)
  • Injury to bowel, bladder or serious injury to cervix (very rare)
  • Repair of damage to cervix, uterus, bladder, bowel or blood
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12
Q

Chlam treatment

A

1g oral Azithromycin (single dose)

OR

100mg oral Doxy- 2 x 7/7days

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13
Q

Gonn treatment

A

250mg IM Ceftriaxone (single dose)
AND
1g oral Azithromycin (single dose)

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14
Q

Genital herpes treatment

A

FIRST EPISODE: 400mg oral aciclovir 3 x (7-10 days)
REPEAT EPISODES: 800 mg oral aciclovir 2 x (3-5 days)

Paracetamol, ibulprofen, sitz bath

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15
Q

Genital warts treatment

A

Podophyllotoxin topical (0.5%)- apply to affected area twice a day for 3 days, then no treatment for 4 days. Can repeat this cycle (3 days on, 4 off) up to 4 cycles.

Imiquimod topical (5%)- apply to the affected area three time a week at bedtime for 16 weeks, leave for 6-10 hours before washing off

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16
Q

Syphilis treatment

A

1.8g IM Benzathine benzylpenicillin (single dose)

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17
Q

What treatments are safe in pregnancy and when breastfeeding for VTE?

A

Unfractionated heparin
LMWH (ie. Tinzaparin)
-> Heparin and LMWH dont cross the placenta

(NOT Warfarin and only give clot busters if life threatening)
- Only exception for warfarin is for women with mechanical prosthetic heart valves and can give between 12-36 weeks.

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18
Q

Treatments for haemorrhageeeeeesss (there are 5)

A

Syntocinon- IV 5unit bolus

Syntometrine- IM Bolus

  • For third stage of labour
  • Combination of Oxytocin 5 units and Ergometrine 500mcg

Misoprostol- PR 800mcg
- Prostaglandin E1

Haemabate (carboprost) - IM 250 mcg

Tranexamic acid - 1g stat iv
- antifibrinolytic

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19
Q

Treatment for ectopic pregnancy

A

Methotrexate

20
Q

Which of the following analgesia are safe in pregnancy?

  • Paracetamol
  • Opiates
  • Entonox
  • NSAIDS
A
  • Paracetamol= YES
  • OPIODS= YES (kinda)- cause neonatal respiratory depression but generally safe inc codeine / diamorphine
  • Enonox- YES
  • NSAIDS= NO NO NO - miscarriage and malformation in 1st trimester, premature closure of the ductus arteriosus in 3rd trimester e.g. don’t give diclofenac- EXCEPTION IS LOW DOSE ASPIRIN
21
Q

What do you prescribe for UTI in pregnancy?

A

Cephalosporins and penicillins safe
(examples of cephalosporins: cefalexin, cefotaxime, meropenem, ertapenem)- BUT avoid co-amoxiclav in pregnancy due to risk of neceroising enterocolitis (NEC) in baby.

  • AVOID trimethoprim in 1st trimester
  • AVOID nitrofuraton in 3rd trimester (can give in 1st and 2nd)
  • AVOID Tetracyclines (tooth decolouration)
22
Q

Treatment for RTI in pregnancy?

A

Penicillins and Macrolides are safe.

23
Q

Treatment for PPROM Preterm Prelabour Rupture of Membranes?

A

Erythromycin 250mg QDS Oral for 10 days to prevent chorioamnionitis

24
Q

Treatment for Chorioamnionitis?

A

Cefuroxime (cephalosporin) 1.5g tds IV
AND
Metronidazole 500mg tds IV

25
Q

Treatment for endometritis in pregnancy?

A

Co-amoxiclav 1.2g IV tds

If allergic to penicillin: Clindamycin (macrolide) + Metronidazole

26
Q

Management for pre-term labour to reduce resp distress?

A

STEROIDS

12mg betamethasone IM
2 doses- 24 hours apart

27
Q

Management to prevent pre-term labour (oxytocin-receptor inhibitor)

A

Prevents labour
Tocolysis- nifedipine or atosoiban for max 24 hours

Can give surgical suture

28
Q

Clinical features of placental abruption and placental praevia - distinguishable features

A

PRAEVIA: no pain, no tenderness, shock consistent with external loss, abnormal lie (transverse, breech or head high), low lying placenta on US

ABRUPTION: pain, MAYBE blood loss- shock inconsistent with external blood loss, normal lie, normal US

29
Q

Preterm delivery occurs between x weeks?

A

24-37 weeks

30
Q

Abx for prevention of infection in PPROM?

A

Erythromycin

Note: co-amoxiclav is contraindicated!

31
Q

What is used to delay labour for steroid injections?

A

Tocolysis: nifedipine or atosiban

32
Q

Postpartum contraceptive option
ALL WOMEN

Time frame for IUD?

A

delivery-> 48hours

4weeks ->

33
Q

Postpartum contraceptive option
ALL WOMEN

Time frame for Diaphragm/cervical cap?

A

6 weeks post delivery ->

34
Q

Postpartum contraceptive option
ALL WOMEN

Time frame for Female sterilisation?

A

delivery -> 1 week (?)

6weeks ->

35
Q

Postpartum contraceptive option
ALL WOMEN

Time frame for Emergency cont?

A

4 weeks ->

36
Q

Postpartum contraceptive option
BREAST FEEDING WOMEN

Time frame for Lactational amenorrhea method?

A

delivery -> 6 months

37
Q

Postpartum contraceptive option
BREAST FEEDING WOMEN

Time frame for POP?

A

6 weeks ->

38
Q

Postpartum contraceptive option
BREAST FEEDING WOMEN

Time frame for COP?

A

6 months ->

39
Q

Postpartum contraceptive option
NON- BREAST-FEEDING WOMEN

Time frame for POP?

A

From delivery

40
Q

Postpartum contraceptive option
NON- BREAST-FEEDING WOMEN

Time frame for COP?

A

3 weeks ->

41
Q

Weeks of antenatal appointments for primips?

A
Formal antenatal visit
11+0-13+6 (dating scan +/- combined screening)
16
20
25- primp only
28
31- primp only
34
36
38
40
41
42
Q

Weeks of antenatal appointments for multips?

A
Formal antenatal visit
11+0-13+6 (dating scan +/- combined screening)
16
20
28
34
36
38
40
41
43
Q

Trisomys of Edwards and Pataus?

A

Edwards= 18

Pataus =13

44
Q
Time frame for:
Combined screening
Chorionic villus sampling 
Amniocentesis
Quadruple test
A
Time frame for:
Combined screening: 11 - 13+6
Chorionic villus sampling: 11-14
Amniocentesis: 15+
Quadruple test: 14-20 (only for Downs)
45
Q

Prophylaxis for VTE in pregnancy?

A

enoxaparin 1mg/kg daily

OR

Dalteparin 100 units/kgs BDS

46
Q

Treatment for PID if gonorrhoea suspicion is high

A

Add

47
Q

Treatment for PID if gonorrhoea suspicion is low

A

Add