Goodpasture's syndrome Flashcards
1
Q
What is it?
A
anti-GBM abs against type IV collagen
2
Q
How does it present?
A
pulmonary haemorrhage
rapidly progressive glomerulonephritis
3
Q
What factors increase likelihood of pulmonary haemorrhage?
A
smoking
LRTI
Pulmonary oedema
Young male
4
Q
wHat are the investigations?
A
reanl biopsy - linear IgG deposits along BM
5
Q
What is the management?
A
plasma exchange
steroids
cyclophosphamide