Gonorrhoea Flashcards

1
Q

Gonorrhoea is a common STI in the UK. It is caused by Neisseria Gonorrhoea, a gram negative bacteria that infects columnar and transitional mucosal cells. Which one of the following are NOT typically affected by gonorrhoea?

1 - urethra
2 - endocervix
3 - fallopian tubes
4 - rectum
5 - pharynx
6 - conjunctiva

A

3 - fallopian tubes

  • genitourinary is most common, followed by rectum and pharynx
  • rectum is higher in gay men
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2
Q

Neisseria Gonorrhoea can be spread in which of the following ways?

1 - unprotected vaginal sex
2 - unprotected anal sex
3 - unprotected oral sex
4 - sharing of sex toys
5 - all of the above

A

5 - all of the above

  • gonorrhoea is very common in gay men
  • infection is 2:1 in favour of men
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3
Q

Neisseria Gonorrhoea has been shown to have some antibiotic resistance. What is the primary reason for this?

1 - antigens are specific to tissue infected
2 - mixes with chlamydia
3 - antigens change every time it infects a host
4 - all of the above

A

4 - all of the above

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4
Q

Gonorrhoea is a most common STI in the UK. It is caused by Neisseria Gonorrhoea, a gram negative bacteria that infect columnar and transitional mucosal cells. Which age group are more at risk of infection?

1 - 15-24
2 - 24-35
3 - 30-40
4 - >50

A

3 - 30-40

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5
Q

Neisseria Gonorrhoea causes gonorrhoea. Do infected patients always present with symptoms?

A
  • No
  • 50% of females can be asymptomatic
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6
Q

Neisseria Gonorrhoea causes genital infections. Males typically present with all of the following. Which is least likely in males?

1 - Urethral discharge (purulent or mucopurulent)
2 - Dysuria
3 - Increased urination frequency
4 - Testicular pain or swelling (epididymitis)
5 - Lower abdominal pain

A

5 - Lower abdominal pain
- more common in women

  • urethritis is common
  • conjunctivitis can occur but is uncommon
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7
Q

Following infection, which of the following is least likely to be a complication of infection with gonorrhoea in men?

1 - epididymo-orchitis
2 - prostatitis
3 - Rectal gonorrhoea:
4 - Pharyngeal gonorrhoea
5 - PID

A

5 - PID
- common in women

Pharyngeal gonorrhoea
- sort throat and difficulty swallowing

Rectal gonorrhoea:
- Anal discharge
- Anal itching
- Painful bowel movement

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8
Q

Neisseria Gonorrhoea causes genital infections. Females typically present with all of the following. Which is least likely in females?

1 - Vaginal discharge (purulent or mucopurulent)
2 - Dysuria
3 - Lower abdominal pain
4 - urethral discharge
5 - Abnormal vaginal bleeding (intermenstrual or postcoital)

A

4 - urethral discharge
- more common in men

  • conjunctivitis can occur but is uncommon
  • infection can lead to PID and infertility
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9
Q

To diagnose Gonorrhoea a swab can be grown on culture. Which of the following media needs to be used?

1 - blood agar
2 - chocolate agar
3 - Xylose Lysine Deoxycholate agar
4 - mycoplasm agar

A

2 - chocolate agar

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9
Q

Which of the following is the gold standard for diagnosing Gonorrhoea?

1- nucleic acid amplification tests (NAATs)
2 - urinalysis
3 - gram positive staining
4 - serology

A

1- nucleic acid amplification tests (NAATs)
- essentially PCR for bacterial genetic info

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10
Q

Nucleic acid amplification tests (NAATs) is the 1st line test for diagnosing gonorrhoea. Which 2 are the best sample to take from a women using NAATs?

1 - cervical swab
2 - vaginal swab
3 - first void urine
4 - hysteroscopy biopsy

A

1 - cervical swab
2 - vaginal swab

Vaginal is best though

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11
Q

Nucleic acid amplification tests (NAATs) is the 1st line test for diagnosing chlamydia and gonorrhoea. What is the best sample to take from a man using NAATs?

1 - cervical swab
2 - vaginal swab
3 - first void urine
4 - hysteroscopy biopsy

A

3 - first void urine

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12
Q

If a swab of a patient with gonorrhoea was added to a slide and placed under a microscope following gram staining, what would we expect to see?

1 - diplococci with a purple colour
2 - diplococci with a pink colour
3 - coccobacilli with a purple colour
4 - coccobacilli with a pink colour

A

2 - diplococci with a pink colour

  • infection typically shows that the pink diplococci are inside neutrophils
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13
Q

When managing a patient who has been diagnosed with gonorrhoea, which of the following must be implemented:

1 - Partner Notification & Treatment
2 - Education, health promotion
3 - Abstinence – 7 days AND until partner treated
4 - Antibiotic treatment
5 - Condoms
6 - Prevention and risk reduction
7 - all of the above

A

7 - all of the above

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14
Q

What is the 1st line medication when treating a patient with a confirmed diagnosis of gonorrhea?

1 - cephalexin 1g
2 - ceftriaxone 1g
3 - doxycycline 100mg
4 - benzathine penicillin 10mg

A

2 - ceftriaxone 1g
- given stat via IM

  • followed by oral ciprofloxacin 500mg in a single dose
  • cephalasporin that are able to inhibit cell wall synthesis
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