gonadotropins

Question 1

What are the 2 gonadotropins?

Answer 1

Luteinizing hormone (LH), Follicle Stimulating Hormone (FSH)

Question 2

What is the function of FSH in males?

Answer 2

Acts in Sertoli cells in the testes to support sperm maturation

Question 3

What is the function of FSH in females?

Answer 3

Promotes the growth an maturation of ovarian follicles and stimulates the production of oestrogen from the ovaries

Question 4

What is the function of LH in males?

Answer 4

Stimulates Leydig cells in the testes to produce testosterone

Question 5

What is the function of LH in females?

Answer 5

Triggers ovulation and stimulates the production of progesterone from the corpus luteum

Question 6

What hormone do Sertoli cells in the testes secrete in response to FSH stimulation?

Answer 6

Inhibin

Question 7

What are the negative feedback loops for gonadotropins in males?

Answer 7

Inhibin provides negative feedback to the anterior pituitary.
Testosterone provides negative feedback to the anterior pituitary and the hypothalamus

Question 8

What are the negative feedback loops for gonadotropins in females?

Answer 8

Oestrogen and Progesterone both provide negative feedback to the anterior pituitary and hypothalamus

Question 9

What condition arises from insufficient production of LH/FSH?

Answer 9

hypogonadism

Question 10

What condition arises when LH and FSH are high at an inappropriately young age?

Answer 10

Precocious puberty

Question 11

Excess secretion of which hormone is associated with PCOS?

Answer 11

LH

Question 12

What is Kallman’s syndrome?

Answer 12

A failure of the hypothalamus to secrete enough GnRH, causing secondary hypogonadism