GN 4 VLVR DS Flashcards

1
Q

Causes of acute vulvar pruritus and irritation EXCEPT

a. allergic contact dermatitis
b. irritant contact dermatitis
c. candidiasis
d. psoriasis

A

D (chronic)

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2
Q

Causes of chronic vulvar pruritus and irritation except

a. allergic contact dermatitis
b. irritant contact dermatitis
c. candidiasis
d. HPV
e. trichomoniasis

A

E (acute

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3
Q

Acute causes of vulvar pruritus (infectious)

5

A
MaCaTi ShaDo
Molluscum contagiosum
Candidiasis
Trichomoniasis
Scabies
Human papilloma virus
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4
Q

Neoplastic differential diagnoses of vulvar pruritus (2)

A

Paget disease

Vulvar cancer

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5
Q

Where are the Bartholin gland drainage located?

A

ducts 2 cm long located at the entrance of the vagina at 5 and 7 o’clock, in the groove between hymen and labia minora

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6
Q

Location of mesonephric cysts

A

more anterior and cephalad in the vagina

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7
Q

location of epithelial inclusion cyst

A

more superficial

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8
Q

True about Bartholin duct cysts

a. most are asymptomatic
b. may vary from 1 to 8 cm in diameter
c. most are unilocular
d. treatment of choice is marsupilization in all patients

A

A-C
D. marsupialization is for women younger than 40, women older than 40 with persistent deep infection, multiple recurrences, recurrent enlargement of gland, excision of a bartholin duct and gland is indicated.

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9
Q

T/F it is best to use regional block or geeral anesthesia for excision of bartholin duct cyst

A

T

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10
Q

most contagious of all STIs

A

pediculosis pubis

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11
Q

etiologic agent of pediculosis pubis

A

crab louse a.k.a pubic louse,

Phthirus pubis

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12
Q

predominant clinical symptom of louse infestation of pediculosis pubis

A

constant pubic pruritus

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13
Q

what causes constant pubic pruritus in pediculosis pubis

A

allergic sensitization

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14
Q

Etiologic agent of scabies

A

Sarcoptes scabiei

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15
Q

Infection is widespread all over the body

a. scabies
b. pediculosis pubis
c. both
d. neither

A

A

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16
Q

what is the predominant clinical symptom of scabies

A

severe but intermittent itching (unlike pediculosis scabies: constant pubic pruritus)

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17
Q

pathognomonic sign of scabies

A

burrow in the skin

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18
Q

Treatment of pediculosis pubis per CDC guidelines

A

permethrin, 1% cream rinse, pyrethrins, with
piperonyl butoxide applied to affected areas and washed off after 10 minutes
* do not apply on eyelids

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19
Q

Treatment of scabies per CDC guidelines

A
Permethrin 5% cream applied to all areas of
the body (8 to 14 hours)
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20
Q

Oral treatment for scabies

A

ivermectin, 200 microgram/kg orally, repeated in 2 weeks if necessary

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21
Q

To avoid reinfection of pediculosis pubis or scabies, treatment should be prescribed for sexual contacts within the previous _____, Include close household contacts

A

6 weeks

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22
Q

chronic localized infection consisting of flesh-colored, dome-shaped papules with an umbilicated center

A

molluscum contagiosum

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23
Q

Incubation period of molluscum contagiosum

A

2-7 weeks

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24
Q

genital ulcers (6)

A
Love DCHS
L  ymphogranuloma Venereum
D onovanosis
C hancroid
H erpes
S yphilis
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25
Q
Incubation period 
Syphilis: \_\_\_\_
Herpes: \_\_\_\_
Chancroid: \_\_\_\_
Lymphogranuloma venereum: \_\_\_\_
Donovanosis: \_\_\_\_\_\_
A
Syphilis: 2-4 wk
Herpes: 2-7 days
Chancroid: 1-14 days
Lymphogranuloma venereum: 3 days- 6wk
Donovanosis: 1-4wk
26
Q
Primary lesion
Syphilis: \_\_\_\_
Herpes: \_\_\_\_
Chancroid: \_\_\_\_
Lymphogranuloma venereum: \_\_\_\_
Donovanosis: \_\_\_\_\_\_
A
Syphilis: Papule
Herpes: Vesicle
Chancroid: Papule or pustule
Lymphogranuloma venereum: papule, pustule, or vesicle
Donovanosis: papule
27
Q
Diameter (mm)
Syphilis: \_\_\_\_
Herpes: \_\_\_\_
Chancroid: \_\_\_\_
Lymphogranuloma venereum: \_\_\_\_
Donovanosis: \_\_\_\_\_\_
A
Syphilis:5-15 mm
Herpes: 1-2 mm
Chancroid: 2-20 mm
Lymphogranuloma venereum: 2-10 mm
Donovanosis: Variable
28
Q
Edges
Syphilis: \_\_\_\_
Herpes: \_\_\_\_
Chancroid: \_\_\_\_
Lymphogranuloma venereum: \_\_\_\_
Donovanosis: \_\_\_\_\_\_
A

Syphilis: sharply demarcated elevated, round, oval
Herpes: erythematous
Chancroid: undermined, ragged, irregular
Lymphogranuloma venereum: elevated, round or oval
Donovanosis: elevated, irregular

29
Q
Induration
Syphilis: \_\_\_\_
Herpes: \_\_\_\_
Chancroid: \_\_\_\_
Lymphogranuloma venereum: \_\_\_\_
Donovanosis: \_\_\_\_\_\_
A
Syphilis: Firm
Herpes: None
Chancroid: Soft
Lymphogranuloma venereum: Occassionally firm
Donovanosis: Firm
30
Q
Pain
Syphilis: \_\_\_\_
Herpes: \_\_\_\_
Chancroid: \_\_\_\_
Lymphogranuloma venereum: \_\_\_\_
Donovanosis: \_\_\_\_\_\_
A
Syphilis: unusual
Herpes: common
Chancroid: usually very tender
Lymphogranuloma venereum: variable
Donovanosis: uncommon
31
Q
Lymphadenopathy
Syphilis: \_\_\_\_
Herpes: \_\_\_\_
Chancroid: \_\_\_\_
Lymphogranuloma venereum: \_\_\_\_
Donovanosis: \_\_\_\_\_\_
A

Syphilis: firm, nontender, pseudoadenopathy bilateral
Herpes: firm, tender, often bilateral
Chancroid: tender, may supurate usually unilateral
Lymphogranuloma venereum: tender, may suppurate, loculated, usually unilateral

32
Q

Treatment for herpes simplex virus in the nonpregnant patient, antiviral agents (3)

A

Valacyclovir
Acyclovir
Famciclovir

33
Q

Treatment for herpes simplex virus First clinical episode

A

Valacyclovir
- 1000mg bid, 7-10 days

Acyclovir
-200mg five times/day or 400 mg tid, 7-10 days

Famciclovir
250 mg tid, 7-10 days

34
Q

Treatment for herpes simplex virus Recurrent clinical episode

A

Valacyclovir
- 1000mg daily, 5 days, or 500 mg bid, 3 days

Acyclovir
- 400 mg tid, 5 days; 800 mg bid, 5 days or 800 mg tid, 2 days

Famciclovir
125 mg bid, 5 days
500 mg once then 250 mg bid 2days
1000 mg bid 1 day

35
Q

Treatment for herpes simplex virus Daily suppressive

A

Valacyclovir
- 1000mg daily, >= 10

Acyclovir
- 400 mg bid

Famciclovir
250 mg bid

36
Q

Granuloma inguinale a.k.a

A

Donovanosis

37
Q

Chronic infection of lymphatic tissue produced by Chlamydia trachomatis

A

Lymphogranuloma venereum

38
Q

Etiologic agent of chancroid

A

Haemophilus ducreyi

39
Q

Etiologic agent of syphilis

A

Treponema pallidum

40
Q

The following are potential causes of biologic false positive results in syphilis serology EXCEPT

a. pregnancy
b. smallpox
c. typhoid fever
d. varicella
e. NOTA

A

E all are answers

41
Q

Etiologic agent of Donovanosis

A

Klebsiella granulomatis

42
Q

T/F Granuloma inguinale can be spread via sexual and nonsexual contact

A

T

43
Q

Treatment for Donovanosis (CDC recommendation)

A

azithromycin 1 g orally once a week or 500
mg daily for 3 weeks and until all lesions
have healed

44
Q

Alternative antibiotic regimens for donovanosis include the

following:

A

doxycycline, 100 mg orally, twice daily for
a minimum of 3 weeks;

ciprofloxacin, 750 mg orally twice daily;

erythromycin base, 500 mg orally four
times daily;

trimethoprim-sulfamethoxazole (TMPSMZ),
one double-strength tablet orally
twice daily.

45
Q

chronic infection of lymphatic tissue

produced by Chlamydia trachomatis

A

Lymphogranuloma Venereum

46
Q

C. trachomatis serotypes causing Lymphogranuloma venereum

A

L1, L2, L3

47
Q

A classic clinical sign of LGV is a depression

between groups of inflamed nodes. What do you call this?

A

double

genitocrural fold, or groove sign

48
Q

How to establish diagnosis of lymphogranuloma venereum

A
Diagnosis is established by detecting C.
trachomatis by culture, direct
immunofluorescence, or nucleic acid
detection from the pus or aspirate from
a tender lymph node.
49
Q

Treatment of LGV

A

100 mg twice
daily for at least 21 days, as the preferred
treatment.

50
Q

The initial lesion is a small papule. How long til the papule evolves into a
pustule and subsequently ulcerates?

A

48-72 hours

51
Q

Treatment of Chancroid?

A

azithromycin, 1 g orally in a single dose

52
Q

painless papule

a. primary syphilis
b. secondary syphilis
c. tertiary syphilis

A

A

53
Q

Primary syphilis manifest as painless papule that appears at the site how long after exposure?

A

2-3 weeks

54
Q

chancre or painless ulcer

a. primary syphilis
b. secondary syphilis
c. tertiary syphilis

A

A

55
Q

Chancre (secondary syphilis) spontaneously heal after how long?

A

within 2-6 weeks

56
Q

What percentage of untreated primary syphilis will result in hematogenous dissemination of spirochetes

A

25%

57
Q

Secondary syphilis is a systemic disease
that develops between ______ after the
primary chancre.

A

6 weeks and 6 months (average 9 weeks)

58
Q

The latent stage of syphilis follows the

secondary stage and varies in duration from _______ years

A

2-20 years

59
Q

What percentage of untreated primary, secondary, or latent phases of the disease develops into tertiary syphilis?

A

33%

60
Q

Antibiotic of choice for Syphilis

A

Penicillin G.

Benzathin Pen G IM

61
Q

Approximately 60% of women develop an acute febrile reaction associated with flulike
symptoms such as headache and myalgia within the first 24 hours after parenteral penicillin therapy for early syphilis. This response is known as the _________.

A

Jarisch-Herxheimer reaction

62
Q

What is the established gold standard test for neurosyphilis.

A

NONE