Glycolysis - Mark Flashcards

1
Q

what is glucose

A

two 3C units and ATP

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2
Q

what two things can metabolic pathways be categorised as

A

anabolic or catabolic

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3
Q

what is catabolism

A

degradative pathways

usually energy- yielding

converge to a few end products

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4
Q

what is anabolism

A

biosynthetic pathways

energy requiring

diverge to synthesise many biomolecules

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5
Q

where does energy for anabolism come from

A

solar energy - photoautotrophs

catabolism - heterotrophs

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6
Q

what is the energy currency of the cell

A

Adenosine Triphosphate(ATP)

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7
Q

how is ATP produced

A

light energy (phototrophs) or catabolism (heterotrophs)

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8
Q

what is ATP for

A

• Used to drive biosynthetic reactions (anabolism), motility etc

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9
Q

is catabolism oxidative or reductive

A

oxidative. Substrates lose reducing equivalents, usually H- ions (H+ ions plus electrons) or NAD+ collects electrons released in catabolism

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10
Q

is anabolism oxidative or reductive

A

reductive. Substrates gain reducing equivalents

NAD (P) H provides the electrons for anabolic processes

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11
Q

redox

A

NAD (P)+ / NAD (P) H can be viewed as a redox energy currency

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12
Q

where is potential energy in glucose contained?

A

reduced hydrocarbon bonds

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13
Q

how is the potential energy in glucose used

A

must be oxidised to CO2 and water

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14
Q

how does the potential energy in glucose arise in the blood

A

breakdown of poly- or di-saccharides

synthesis from non-carbohydrate sources

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15
Q

where are the enzymes involved in glycolysis located

A

cytosol

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16
Q

what are the three basic stages in Glycolysis

A
  1. Glucose is destabilised (requires energy – energy investment)
  2. The hexose molecule is cleaved into 2 three carbon molecules
  3. ATP (energy) is generated
17
Q

see powerpoint for

A

glycolysis overview

18
Q

what is the overall reaction of glycolysis

A

Glucose + 2NAD+ + 2ADP + 2Pi  2NADH + 2PYRUVATE + 2ATP + 2H2O + 2H+

19
Q

what is the main oxidising agent in glycolysis

A

NAD+, must be regenerated

20
Q

anaerobic conditions

A

reduced to lactate generates NAD+ from NADH

21
Q

aerobic conditions

A

NADH oxidised in the mitochondria to yield ATP