Glycolysis Flashcards
Is anabolism endergonic or exergonic?
endergonic
Is anabolism oxidative or reductive?
reductive
What drives anabolism in general?
NADPH
What is the terminal electron carrier?
oxygen
What does oxygen undergo to become water?
oxidative phosphorylation
Name the 2 important things glucose is used in the body for
oxidation through aerobic glycolysis to pyruvate
fermentation through anaerobic glycolysis to lactate
Name the passive facilitated glucose transporters
GLUT 1-5
In the first step of aerobic glycolysis what occurs?
glucose phosphorylated at both ends to form fructose-1,6-biphosphate
What happens to fructose-1,6-biphosphate?
split into two and phosphorylated twice
Overall how many times is ATP phosphorylated?
2
What is stage 1 of glycolysis?
glucose trapped and destabilised
What is stage 2 of glycolysis?
two interconvertible 3 carbon molecules formed
What is stage 3 of glycolysis?
generation of ATP
What does hexokinase control?
substrate entry
What does phosphofructokinase control?
rate of flow
What does pyruvate kinase control?
product exit
How does AMP increase use of glycolysis?
using fructose-1,6-biphosphate enzyme
What is energy charge?
ratio of ATP to AMP
What is the Warburg effect?
Up-take of anaerobic glycolysis in cancer cells
