Glycolysis

Question 1

Is anabolism endergonic or exergonic?

Answer 1

endergonic

Question 2

Is anabolism oxidative or reductive?

Answer 2

reductive

Question 3

What drives anabolism in general?

Answer 3

NADPH

Question 4

What is the terminal electron carrier?

Answer 4

oxygen

Question 5

What does oxygen undergo to become water?

Answer 5

oxidative phosphorylation

Question 6

Name the 2 important things glucose is used in the body for

Answer 6

oxidation through aerobic glycolysis to pyruvate

fermentation through anaerobic glycolysis to lactate

Question 7

Name the passive facilitated glucose transporters

Answer 7

GLUT 1-5

Question 8

In the first step of aerobic glycolysis what occurs?

Answer 8

glucose phosphorylated at both ends to form fructose-1,6-biphosphate

Question 9

What happens to fructose-1,6-biphosphate?

Answer 9

split into two and phosphorylated twice

Question 10

Overall how many times is ATP phosphorylated?

Answer 10

2

Question 11

What is stage 1 of glycolysis?

Answer 11

glucose trapped and destabilised

Question 12

What is stage 2 of glycolysis?

Answer 12

two interconvertible 3 carbon molecules formed

Question 13

What is stage 3 of glycolysis?

Answer 13

generation of ATP

Question 14

What does hexokinase control?

Answer 14

substrate entry

Question 15

What does phosphofructokinase control?

Answer 15

rate of flow

Question 16

What does pyruvate kinase control?

Answer 16

product exit

Question 17

How does AMP increase use of glycolysis?

Answer 17

using fructose-1,6-biphosphate enzyme

Question 18

What is energy charge?

Answer 18

ratio of ATP to AMP

Question 19

What is the Warburg effect?

Answer 19

Up-take of anaerobic glycolysis in cancer cells