Glycolysis Flashcards
Step 1
Glucose - Glucose-6-Phosphate
ATP - ADP + H+
Hexokinase is the enzyme
inhibited by: glucose-6-phosphate, glucagon
Step 2
Glucose-6-Phospate - Fructose-6-Phosphate
enzyme is glucose-6-phosphate isomerase
Step 3
Fructose-6-Phosphate - Fructose 1,6 bisphosphate
ATP - ADP + H+
This step is the first committed step
enzyme is phosphofructosekinase-1
inhibited by glucose, phosphoenol pyruvate, and ATP, citrate
activated by ADP and AMP, fructose-2,6-bisphosphate
Step 4
Fructose-1,6-bisphosphate - Dihydroxyacetone phosphate + glyceraldehyde-3-phosphate
enzyme is aldolase
Step 5
Dihydroxyacetone phosphate - Glyceraldehyde-3-phosphate
enzyme is triose phosphate isomerase
Step 6
Glyceraldehyde-3-phosphate - 1,3-bisphosphoglycerate
NAD+ +Pi - NADH + H+
enzyme is glyceraldehyde-3-phosphate dehydrogenase
the first step of the payoff phase
Step 7
1,3-bisphosphoglycerate - 3-phosphoglycerate
ADP - ATP
enzyme is phosphoglycerate kinase
Step 8
3-phosphoglycerate - 2-phosphoglycerate
enzyme is phosphoglycerate mutase
proceeds through 2,3-bisphosphoglycerate intermediate
Step 9
2-phosphoglycerate - phosphoenol pyruvate
enzyme is enolase
Step 10
Phosphoenolpyruvate - pyruvate
ADP + H+ - ATP
Enzyme is pyruvate kinase
activated by fructose-1,6-bisphosphate
inhibited by ATP and glucagon