Glycolysis Flashcards

1
Q

Step 1

A

Glucose - Glucose-6-Phosphate

ATP - ADP + H+

Hexokinase is the enzyme

inhibited by: glucose-6-phosphate, glucagon

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2
Q

Step 2

A

Glucose-6-Phospate - Fructose-6-Phosphate

enzyme is glucose-6-phosphate isomerase

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3
Q

Step 3

A

Fructose-6-Phosphate - Fructose 1,6 bisphosphate

ATP - ADP + H+

This step is the first committed step

enzyme is phosphofructosekinase-1

inhibited by glucose, phosphoenol pyruvate, and ATP, citrate

activated by ADP and AMP, fructose-2,6-bisphosphate

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4
Q

Step 4

A

Fructose-1,6-bisphosphate - Dihydroxyacetone phosphate + glyceraldehyde-3-phosphate

enzyme is aldolase

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5
Q

Step 5

A

Dihydroxyacetone phosphate - Glyceraldehyde-3-phosphate

enzyme is triose phosphate isomerase

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6
Q

Step 6

A

Glyceraldehyde-3-phosphate - 1,3-bisphosphoglycerate

NAD+ +Pi - NADH + H+

enzyme is glyceraldehyde-3-phosphate dehydrogenase

the first step of the payoff phase

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7
Q

Step 7

A

1,3-bisphosphoglycerate - 3-phosphoglycerate

ADP - ATP

enzyme is phosphoglycerate kinase

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8
Q

Step 8

A

3-phosphoglycerate - 2-phosphoglycerate

enzyme is phosphoglycerate mutase

proceeds through 2,3-bisphosphoglycerate intermediate

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9
Q

Step 9

A

2-phosphoglycerate - phosphoenol pyruvate

enzyme is enolase

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10
Q

Step 10

A

Phosphoenolpyruvate - pyruvate

ADP + H+ - ATP

Enzyme is pyruvate kinase

activated by fructose-1,6-bisphosphate

inhibited by ATP and glucagon

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