Glycolysis Flashcards
What’s the end product for glycolysis
Pyruvate
State the 3 regulatory enzymes of glycolysis
1)Hexokinase or glucokinase
2pfk1
3)pyruvate kinase
Elevated concentrations of lactate in the plasma, is termed as
lactic acidosis
The first payoff reaction of glycolysis is ——-?
Reaction 6
Reaction 6 of glycolysis is the first oxidation -reduction reaction of glycolysis ,true/false
True
Glyceraldehyde 3 -phosphate dehydrogenase is inhibited by ——-?
Hyperglycemia
State the enzymes of glycolysis that catalyze the substrate level phosphorylation
Phisphoglycerate Kinase
Pyruvate kinase
Enolase is activated by fluoride ,true/false
False
Fluoride is a potent inhibitor of enolase, true/false
True
Glycolysis takes place in the mitochondria ,T/F
False it takes place in the cell cytosol
The end product of anaerobic glycolysis is pyruvate,true/false
False, the end product of anaerobic glycolysis is suppose to be lactate
———,———and———- are the key enzymes of glycolysis
Pyruvate kinase
Phosphofructokinase-1
Hexokinase/glucokinase
Hexokinase is activated by the following except
a)AMP
b)ADP
C)Glucose 6 phosphate
Glucose 6 phosphate because it inhibits hexokinase
Insulin increases activity of gluts and increases synthesis of hexokinase,TRUE/FALSE
True
Glucokinase is inhibited by fructose 6 phoshate ,true/false
True
Which of the following is true a)glucokinase has a high affinity for glucose
b)hexokinase has a low affinity for glucose
C)glucokinase is inhibited by glucose 6 phosphate
d)hexokinase has a high affinity for glucose
D
PFK-1 is inhibited by following except —
a)low ph(high proton concentration
b)elevated levels of citrate
c)elevated levels of ATP
d) high concentration of AMP
D: the remaining options are inhibitors
PFK 1is activated allosterically by fructose 2, 6 bisphosphate ,true/false
True
The following inhibits pyruvate kinase except
a)ATP
b)alanine
C)fructose 1,6 bisphosphate
C (fructose 1,6 bisphosphate
Exercising skeletal muscle results in
1)in an elevated NADH/NAD+ ratio
2)favoring the reduction of pyruvate to lactate
Glycolysis increases with an increase in ATP ,true or False
False:it increases with a decrease in Atp
We’re does the pentose phosphate pathway occur
In the cytosol
