Glycolysis

Question 1

What’s the end product for glycolysis

Answer 1

Pyruvate

Question 2

State the 3 regulatory enzymes of glycolysis

Answer 2

1)Hexokinase or glucokinase
2pfk1
3)pyruvate kinase

Question 3

Elevated concentrations of lactate in the plasma, is termed as

Answer 3

lactic acidosis

Question 4

The first payoff reaction of glycolysis is ——-?

Answer 4

Reaction 6

Question 5

Reaction 6 of glycolysis is the first oxidation -reduction reaction of glycolysis ,true/false

Answer 5

True

Question 6

Glyceraldehyde 3 -phosphate dehydrogenase is inhibited by ——-?

Answer 6

Hyperglycemia

Question 7

State the enzymes of glycolysis that catalyze the substrate level phosphorylation

Answer 7

Phisphoglycerate Kinase

Pyruvate kinase

Question 8

Enolase is activated by fluoride ,true/false

Answer 8

False

Question 9

Fluoride is a potent inhibitor of enolase, true/false

Answer 9

True

Question 10

Glycolysis takes place in the mitochondria ,T/F

Answer 10

False it takes place in the cell cytosol

Question 11

The end product of anaerobic glycolysis is pyruvate,true/false

Answer 11

False, the end product of anaerobic glycolysis is suppose to be lactate

Question 12

———,———and———- are the key enzymes of glycolysis

Answer 12

Pyruvate kinase
Phosphofructokinase-1
Hexokinase/glucokinase

Question 13

Hexokinase is activated by the following except
a)AMP
b)ADP
C)Glucose 6 phosphate

Answer 13

Glucose 6 phosphate because it inhibits hexokinase

Question 14

Insulin increases activity of gluts and increases synthesis of hexokinase,TRUE/FALSE

Answer 14

True

Question 15

Glucokinase is inhibited by fructose 6 phoshate ,true/false

Answer 15

True

Question 16

Which of the following is true a)glucokinase has a high affinity for glucose
b)hexokinase has a low affinity for glucose
C)glucokinase is inhibited by glucose 6 phosphate
d)hexokinase has a high affinity for glucose

Answer 16

D

Question 17

PFK-1 is inhibited by following except —
a)low ph(high proton concentration
b)elevated levels of citrate
c)elevated levels of ATP
d) high concentration of AMP

Answer 17

D: the remaining options are inhibitors

Question 18

PFK 1is activated allosterically by fructose 2, 6 bisphosphate ,true/false

Answer 18

True

Question 19

The following inhibits pyruvate kinase except
a)ATP
b)alanine
C)fructose 1,6 bisphosphate

Answer 19

C (fructose 1,6 bisphosphate

Question 20

Exercising skeletal muscle results in

Answer 20

1)in an elevated NADH/NAD+ ratio
2)favoring the reduction of pyruvate to lactate

Question 21

Glycolysis increases with an increase in ATP ,true or False

Answer 21

False:it increases with a decrease in Atp

Question 22

We’re does the pentose phosphate pathway occur

Answer 22

In the cytosol