Glycolysis Flashcards

1
Q

Is ATP an unstable compund?

A

no

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2
Q

what is required to break down ATP?

A

enzymes

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3
Q

what is formed during respiration?

A

NADH

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4
Q

is there a direct flow of electrons between glucose and oxygen?

A

no

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5
Q

how do electrons flow during glycolysis?

A

via carrier molecule NADH and through the electron transport chain

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6
Q

what is NADH?

A

NAD^+ plus one proton = NADH = the reduced form of NAD^+

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7
Q

what is the process of glycolysis?

A

where glucose is broken down into two separate pyruvate molecules

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8
Q

what is the net gain of NADH during glycolysis?

A

2

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9
Q

what is the net gain of ATP during glycolysis?

A

2

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10
Q

how many sugars does glucose have?

A

6

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11
Q

how many sugars does a pyruvate molecule have?

A

3

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12
Q

where does glycolysis take place?

A

the cytosol

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13
Q

how is the ATP synthesised?

A

substrate level phosphorylation

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14
Q

how does substrate level phosphorylation work?

A

it is catalysed by a series of enzymes

the substrate is phosphorylated by an enzyme and the Pi is transferred to the ADP attached to the enzyme forming ATP.

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15
Q

when is glycolysis essential and why?

A

it is essential during intense excersize as it is a fast reaction that doesn’t require oxygen.

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16
Q

what happens to pyruvate if oxygen is present?

A

the pyruvate will move into the mitochondria

17
Q

what proteins are present in the inner membrane of the mitochondria?

A

components of the electron transport chain

ATP synthase

18
Q

how many membranes does the mitochondria have?

A

2

19
Q

what are the layers of the mitochondrial membrane?

A

the outer membrane
the inter-membrane
the inner membrane
the matrix

20
Q

what is a key feature of the mitochondria’s inner membrane?

A

it is impermeable to proteins

21
Q

what happens to pyruvate in the mitochondria?

A

it is converted from a 3 carbon sugar to a 2 carbon sugar by means of decarboxylation and NADH is formed.

22
Q

how can the glycolytic pathway be used and improved by biologists?

A

the Warberg effect - some cancerous cells will convert pyruvate into lactate even if O2 is present, scientists believe that disrupting this effect may disrupt cancer growth.