Glycogenesis Flashcards

1
Q

What is faster when energy is needed: glycogenolysis or GNG?

A

glycogenolysis

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2
Q

Storage form and of carbs in animals

A

glycogen granule

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3
Q

Primary storage sites of glycogen are ___ and ___ ___

A

liver, skeletal muscle

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4
Q

Glycogen chains are bonded with with ____

A

a(1-4)

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5
Q

Glycogen branches are bonded with____ and they happen every ___ links

A

a(1-6), 10

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6
Q

Maximum size for a glycogen granule is ____ glucose molecules

A

55,000

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7
Q

Muscle has ___g of glucose for fuel, liver has ____g of glucose for blood glucose

A

400, 100

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8
Q

T/F: Muscle can release glucose back into the blood

A

FALSE

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9
Q

Glycogenesis is initiated by:

A

Glucose-6-phosphate

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10
Q

What is the protein that starts glycogenesis if there is no glycogen fragment? What is the amino acid that accompanies that protein? How about what enzyme?

A

Glycogenin, Tyrosine, Glycogen Initiator Synthase

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11
Q

What are the three energy molecules used to synthesize glycogen?

A

ATP, UTP, pyrophosphatase

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12
Q

What is the enzyme that adds more a(1-4) bonds to the glycogen chain?

A

glycogen synthase

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13
Q

What is the enzyme that adds a(1-6) bonds (branches) to the glycogen chain?

A

glycosyl-(4:6)-transferase

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14
Q

What is the key enzyme in glycogen synthesis?

A

glycogen synthase

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15
Q

Allosteric regulation of glycogenesis is activated by ____

A

glucose-6-phosphate

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16
Q

AMP kinase regulation of glycogenesis by___, ___, and ____

A

glucagon (ONLY IN THE LIVER), epinephrine (liver/muscle), norepinephrine (liver/muscle)

17
Q

What is the primary site of fructose disposal?

A

liver

18
Q

Low-dose fructose causes a ____-fold increase in new liver glycogen synthesis

A

three

19
Q

fructose has no benefit in ___ glycogen synthesis

A

muscle

20
Q

Exercise increases GLUT-_ translcation and _____ glycogen synthesis and _____ insulin sensitivity.

A

4, stimulates, increases

21
Q

T/F: one workout can decrease muscle glycogen

A

True

22
Q

Rapid phase post-exercise glycogen synthesis is insulin _____.

A

independent. rapid happens if carbs are provided immediately after exercise

23
Q

Slow phase post-exercise glycogen synthesis is insulin ____

A

dependent.

24
Q

The window for gains is ___ post-exercise. glycogen synthesis rates may be __% lower when you miss the gains window

A

2 hours, 45%

25
Q

Increased carb intake increases glycogen storage, to a point: diminished returns after ___ kcal of glucose

A

500

26
Q

glycogen storage disease in the liver causes___, in the muscle ____

A

hypoglycemia, weakness

27
Q

Most common Glycogen storage disease is type _

A

1, aka von gierke’s disease

28
Q

What enzyme turns glycogen to glu-1-phos?

A

glycogen phosphorylase

29
Q

What stimulates glycogen phosphorylase?

A

1) Low ATP
2) high ADP, AMP
3) low glucose
4) glucagon
5) muscle contraction