Glukoneogenese Flashcards
Hvad er det hastighedsbegrænsende trin i glukoneogenese
omdannelse af oxaloacetat til phosphoenolpyruvat
Hvad er flux kontrolkoefficient C
Betydningen af hvert enkelt enzym for flux i en pathway
Hvad er elasticitetskoefficient epsilon
effekten af substrater på deres V
Hvad er responskoefficient R
Effekten af ydre stimuli på en metabolisk pathway
when does the hexokinase IV come out of the nucleus and when does it go back to it?
when glucose is high
when fructose 6 phosphate is high
which form of ATP inhibits FBPase 1
AMP
F26bP effekt på PFK1 og FBPase-1
Stimulerende
hæmmende
PCK1
promoter som koder for glukose 6 phosphatase og PEP carboxykinase
stimuleres af foxo1 uden phosphater
alanine, aspartate and glutamine can be converted to which intermediates in gluconeogenesis?
to pyruvate
to oxaloacetate
alpha ketoglutarate
what is a positive effector on pyruvat carboxylase
aceteyl-CoA
In which case is the mitochondrial isozyme of PEP carboxykinase is used?
when lactate is transformed pyruvate
Why is gluconeogenesis costly
to ensure the irreversibility of it
In adipocytes which enzyme is missing from glyceroneogenesis pathway
glycerol kinase
hexokinase IV has a very ….. KM
high
hexokinase IV is subject to inhibition by …
reversbile binding of fructose 6-fosfat
