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Farmacologia Dr Prieto > Glucosidos cardiacos > Flashcards

Glucosidos cardiacos Flashcards

1
Q

Glucosidods cardiacos

A

Digoxina

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2
Q

Mecanismo de acción Digoxina

A

Inhibición bomba Na/K ATPasa cardiaca con aumento de Na intracelular y expulsión de Ca, con aumento de Ca intracelular y efecto inotrópico positivo.

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3
Q

EA Digoxina

A

> 1.2 ng/ml –> mortalidad
Causas de toxicidad: LRA y sobredosis
Arritmias (en sanos: bradicardia, Fa y BAV; en cardiopatas: EV, bigeminismo, TV y FV), manifestaciones GI y neurotoxicas

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4
Q

Antidoto sobredosis

A

Inmunoterapia fragmentos Fab antidigoxina

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Farmacologia Dr Prieto (11 decks)

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