Glucose Homeostasis Flashcards

1
Q

Alpha cells pancreas respond to what

A

Hypoglycemia only

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2
Q

Alpha cells pancreas release what hormone

A

Glucagon

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3
Q

Alpha cells pancreas target what organ

A

Liver and Adipose

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4
Q

When Alpha cell target the Liver, what pathway is increases?

A

Glycogenolysis
Gluconeogenesis
Beta Oxidation of fats termed
Ketogenesis

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5
Q

When Alpha cell target the Adipose, what pathway is increased?

A

Lipolysis

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6
Q

The hypothalamus responds to what

A

Hypoglycaemia PLUS exercise or sleep

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7
Q

The hypothalamus releases what hormone

A

Growth Hormone

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8
Q

When the hypothalamus targets the Liver, what pathway is increased?

A

GH is converted to Insulin like Growth Factor 1 AKA Somatomedin C

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9
Q

When the hypothalamus targets the muscle, what pathway is increased?

A

Increases
-Amino acid uptake
-proteins synthesis
-beta oxidation fats

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10
Q

When the hypothalamus targets the muscle, what pathway is Decreased?

A

Decreases:
Protein Breakdown
Carbohydrate
Metabolism

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11
Q

The hypothalamus target what organs

A

-Liver
-muscle responds to somatomedian C and growth hormone

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12
Q

Adrenal medulla responds to what

A

Hypoglycemia PLUS acute stress

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13
Q

What happens when you wake up stressed

A

You become hypoglycaemic which causes your body to make epinephrine

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14
Q

What hormone is released in the Adrenal medulla

A

Epinephrine

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15
Q

The adrenal medulla targets what organs?

A

Liver
Adipose
Muscle

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16
Q

The adrenal medulla and cortex targets the liver which increases what pathway?

A

Glycogenolysis
Gluconeogenesis
Beta oxidation of fats termed Ketogenesis

16
Q

The adrenal medulla targets the Muscle which increases what pathway?

A

Glycogenolysis
krebs Cycle
Beta oxidation of fats

16
Q

The adrenal medulla and cortex targets the Adipose which increases what pathway?

A

Lipolysis

16
Q

The adrenal cortex targets the Muscle which increases what pathway?

A

Blocks the Glut 4 transporter

16
Q

Adrenal cortex targets what organs

A

Liver
Muscle
Adipose

17
Q

Adrenal cortex responds to what

A

Chronic stress and does not need hypoglycaemia to be released

18
Q

The adrenal cortex releases what hormone?

A

Cortisol

19
Q

Beta cells pancreas responds to what?

A

Hyperglycaemia

20
Q

Beta cells pancreas release what hormone?

A

Insulin

21
Q

Beta cells pancreas target what organs?

A

Liver, Adipose, muscle

22
Q

Beta cells pancreas target the liver which increases what pathway(s)?

A

Glycogenesis
Glycolysis
Triacylglycerol (TAG) Synthesis
Cholesterol synthesis

23
Q

Beta cells pancreas target the Adipose which increases what pathway(s)?

A

Stimulates Glut 4 transporter and glucose enters TAG STORAGE

24
Q

Beta cells pancreas target the Muscle which increases what pathway(s)?

A

-Stimulates Glut 4 transporter and glucose enters
- glycogenesis
-Glycolysis
-Krebs
-ETC

25
Q

Delta cells pancreas and Hypothalamus responds to what?

A

Hyperglycemia

26
Q

Delta cells pancreas and Hypothalamus release what hormone

A

Somatostatin

27
Q

The Delta cells pancreas target what organs?

A

Hypothalamus and Anterior Pituitary

28
Q

Once the Delta cells pancreas target the Hypothalamus and Anterior Pituitary, What is effected?

A

Decreases the release of the of GHRH and GH (growth hormone)