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Antibióticos > Glucopeptidos > Flashcards

Glucopeptidos Flashcards

1
Q

Cuales son los farmacos pertenecientes a esta classe ?

A 
Vancomicina 
Teicoplanina
Bacitricina 
Fosfomicina 
Cicloserina
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2
Q

Clasificación

A 
GLUCOPEPTDOS 
Vancomicina 
Teicoplanina 
POLIPEPTIDIOS 
Bacitricina 
OTROS 
Fosfomicina 
Cicloserina
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3
Q

Mecanismo de acción de la Vancomicina

A

Inibción de la enzima Transglucosilasa que por su vez inibe la associación disacarido alanina
Destrucción de ARN

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4
Q

Qual el espectro de la vancomicina

A 
G+
MRSA
S. epidermidis
S. Haemoliticus
Enterococo
C. Difficile 
B. Anthracs 
Actinom,yces 
C. Diphyteriae 
L. Monocitogenes
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5
Q

Mecanismo de resistencia a la vancomicina

A

La alteración del sitio de acción: D-alanil-lactato

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6
Q

Farmacocinetica de la vancomicina

A 
A= IV, IM y VO
D= Gereral pero inconstante en LCR y bilis 
E= Renal
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7
Q

Reacciones adversas de la Vancomicina

A 
Sx del Cuello Rojo
Ototoxicidad 
Prurito
Macula 
Hiperemia
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8
Q

Buenos farmacos para corelacionar a la vancomicina

A

Aminoglucosidos
Cefalosporinas
B-Lactamicos

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9
Q

Malos farmacos para associar a la vancomicina

A

Cloranfenicol
Heparina
Meticila
Corticoesteroides

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10
Q

Indicaciones de la Vancomicina

A

Endocarditis por MRSA, Enterococo
Colitis Pseudomembranosa por C. Difficile
Meningitidis por Carynebacteriumy flavobacterium

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11
Q

Qual la sugestión de la ultilización de la teicoplanina

A

Por sus menores efectos adversos

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12
Q

Mecanismo de acción de la Bacitricina

A

Inibidor de transportador de lipidos (Bactoprenol)

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13
Q

Adm de la bacitricina

A

Topica

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14
Q

Espectro de la Bacitricina

A

G+ Coco y Bacilos

Coco G-

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15
Q

Indicaciones de la bacitracina

A 
Sx de la piel escaldad 
Impetigo 
Foliculitis 
Eripsela 
Colitis Ps 
Conjuntivitis
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16
Q

Mecanismo de acción de la fosfomicina

A

Inibición de la enzima fosfoenol piruvato sintetasa (Acción en la sintesis dfe la pared celular)

17
Q

Farmacocinetica de la Fosfomicina

A 
A= Oral 
D= Vias urinarias 
E= Renal
18
Q

Espectro de la Fosfomicina

A

Coco G+
MRSA
BG-

19
Q

Mecanismo de acción de la cicloserina

A

Efecto Competitivo contra la alanina transferasa

20
Q

Espectro d ela cicloseria

A

BAAR
MSSA
BG-

21
Q

Farmacocinetica de la cicloserina

A

A= Cicloserina
D: Liquido pleural, Esputo, Bilis y SNC
M Hepatico
E= Renal

Antibióticos (12 decks)

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