Fenicoles Flashcards

1
Q

Farmacos que componem los fenicoles

A

Cloranfenicol y Tianfenicol

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2
Q

Mecanismo de acción de los Fenicoles

A

Acción sobre los Rib 50s

Inibe sintesis de proteinas

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3
Q

Mecanismo de resistencia de los fenicoles

A

Enzimas inactivantes

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4
Q

Espectros de los fenicoles

A

G+ (Bacilos, Strepto y aureus y Cocos Anab, Prolongaciones Anaerobios)
G- (Neisserias, Cocobacilos, B- y H. Pilory)
Espiroquetas (Borrelia y Treponema)

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5
Q

Farmacocinetica

A

A= IV,T y O
D= General
M= Heptico
Escreción Renal

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6
Q

Reaciones Ad

A

Citopenia global
Aplasia medular
Neuropatia optica
Sx del niño Gris

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7
Q

Indicaciones

A

Meningitis
Basesso cerebral
Inf. Por anaerobios

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