glucocorticoids Flashcards
what endocrine gland produces natural glucocorticoids
adrenal cortex
why the inflammation process my occur
glucocorticoids inhibit prostaglandins formation
therapeutic uses of glucocorticoids
anti-inflammatory
decrease scar tissue
immunosuppressive
tx neurologic shock
common side effects
polydipsia
polyuria
polyphagia
weight gain
inc BG
inc gastic acid
dec mucus production
adverse reactions
immune response depression
delayed wound and fracture healing
anemia
purpose and use of (1)aqueous and (2)suspension forms
- can be given IV
rapid onset
(emergency and salt added) - prolonged action
IM or SQ
short acting
hydrocortisone (topical)
medium acting
triamcinolone
prednisone
prednisolone
prednisolone sodium succinate
long acting
dexamethasone
dexamethasone sodium phosphate
(emergencies)
hemogram changes
dec: lymphs and eos
inc: neuts and platelets
exogenous
added from an outside source
endogenous
produced from within; naturally occurring
iatrogenic
caused by medical treatment
cushings disease
too much glucocorticoid (natural response)
hyperadrenocorticism
creates cushings induced by meds with steroids
Addisons disease
too little glucocorticoid; natural response
hypoadrenocorticism
sudden stop of steroids and endogenous steroids aren’t being created - leads to Addisons disease
anabolic
builds
catabolic
breaks down
glucocorticoids
corticosteroids produced by adrenal cortex (catabolic)
corticosteroids
anti-inflammatory steroids
