glucocorticoids Flashcards

1
Q

what endocrine gland produces natural glucocorticoids

A

adrenal cortex

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2
Q

why the inflammation process my occur

A

glucocorticoids inhibit prostaglandins formation

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3
Q

therapeutic uses of glucocorticoids

A

anti-inflammatory
decrease scar tissue
immunosuppressive
tx neurologic shock

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4
Q

common side effects

A

polydipsia
polyuria
polyphagia
weight gain
inc BG
inc gastic acid
dec mucus production

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5
Q

adverse reactions

A

immune response depression
delayed wound and fracture healing
anemia

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6
Q

purpose and use of (1)aqueous and (2)suspension forms

A
  1. can be given IV
    rapid onset
    (emergency and salt added)
  2. prolonged action
    IM or SQ
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7
Q

short acting

A

hydrocortisone (topical)

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8
Q

medium acting

A

triamcinolone
prednisone
prednisolone
prednisolone sodium succinate

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9
Q

long acting

A

dexamethasone
dexamethasone sodium phosphate
(emergencies)

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10
Q

hemogram changes

A

dec: lymphs and eos
inc: neuts and platelets

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11
Q

exogenous

A

added from an outside source

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12
Q

endogenous

A

produced from within; naturally occurring

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13
Q

iatrogenic

A

caused by medical treatment

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14
Q

cushings disease

A

too much glucocorticoid (natural response)

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15
Q

hyperadrenocorticism

A

creates cushings induced by meds with steroids

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16
Q

Addisons disease

A

too little glucocorticoid; natural response

17
Q

hypoadrenocorticism

A

sudden stop of steroids and endogenous steroids aren’t being created - leads to Addisons disease

18
Q

anabolic

A

builds

19
Q

catabolic

A

breaks down

20
Q

glucocorticoids

A

corticosteroids produced by adrenal cortex (catabolic)

21
Q

corticosteroids

A

anti-inflammatory steroids