antifungals

Question 1

2 types of fungal infections

Answer 1

Dermatomycoses (superficial)
Systemic mycoses (more severe)

Question 2

blastomycosis

Answer 2

• type of systemic mycoses
• chronic coughing, skin lesions, weight loss, fever

Question 3

fungistatic

Answer 3

inhibits growth of fungus

Question 4

cryptococcus and histoplasmosis

Answer 4

type of blastomycosis

Question 5

mycosis

Answer 5

diseases caused by fungus

Question 6

dermatomyocosis

Answer 6

ringworm
- superficial fungal infection (skin, hair, nails)

Question 7

fungicidal

Answer 7

kills fungus

Question 8

antimycotic agent

Answer 8

destroys or prevents growth of fungi

Question 9

local infection

Answer 9

in a specific area only

Question 10

generalized infection

Answer 10

the same thing all over the body

Question 11

systemic infection

Answer 11

in bloodstream - affect whole body

Question 12

symptoms of nephrotoxicity

Answer 12

kidney failure, urinary issues

Question 13

cause and tx of dermatomycosis

Answer 13

yeast infections, skin lesions;
- griseofulvin
- ketoconazole
- terbinafine

Question 14

cause and tx of systemic mycoses

Answer 14

lung issues, skin lesions, fever, wt loss;
- itraconazole
- fluconazole
- amphotericin-B

Question 15

ketoconazole

Answer 15

• used for fungal and yeast skin infections
• topical for dermatomycosis

Question 16

miconazole

Answer 16

topical tx for dermatomycosis

Question 17

thiabendazole

Answer 17

topical tx for dermatomycosis

Question 18

griseofulvin

Answer 18

• used for fungal infection in the skin
• causes teratogen (birth defects) in cats
• dermatomycosis tx

Question 19

terbinafine

Answer 19

• newer drug that is a cheaper alternative to Ketoconazole
• avoid in animals with hepatic disease
• dermatomycosis tx

Question 20

itraconazole

Answer 20

• used for skin and systemic infections
• best anti-fungal for cats
• expensive
• treat for one-month past resolution of clinical signs
• should not be compounded

Question 21

fluconazole

Answer 21

• cheaper alternative to Itraconazole but may not work as well
• safer for patients with liver disease
• systemic mycoses tx

Question 22

amphotericin b

Answer 22

• used as last resort for systemic infections
• severe side effects including nephrotoxicity
• must be given IV or will cause tissue necrosis
• must be reconstituted