GLP-1 Agonist

Question 1

Dulaglutide

Answer 1

Trulicity

Question 2

Exenatide

Answer 2

Bydureon
Byetta 10 MCG Pen
Byetta 5 MCG Pen

Question 3

Liraglutide

Answer 3

Saxenda

Victoza

Question 4

Mechanism of action

Answer 4

Dulaglutide is a glucagon-like peptide (GLP-1) receptor agonist. Insulin release is stimulated in a glucose-dependent manner via activation of GLP-1 receptors on pancreatic beta cells. Glucagon secretion is also reduced and gastric emptying is delayed; thereby reducing the rate at which postprandial glucose appears in circulation. GLP-1 regulates appetite and calorie intake, including via receptors that are present in the brain. The weight reduction effect of liraglutide is due to decreased calorie intake.

Question 5

Albiglutide

Answer 5

Tanzeum