Glomerulonephritis Flashcards

1
Q

Clinicopathologic correlate of RPGN

A

Crescentic GN

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2
Q

Pulmonary-renal syndrome consists of lung hemorrhage in combination with anti-GBM nephritis presenting as RPGN

A

Goodpasture’s

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3
Q

“Flea-bitten” appearance of kidneys on gross pathology due to subcapsular hemorrhages

A

Subacute bacterial endocarditis

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4
Q

GN occurring with IE, shunt infections or intraabdominal or pelvic abscesses

A

Immune complex GN

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5
Q

MC GN worldwide

A

IgA nephropathy/Berger’s

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6
Q

Vasculitis closely associated with IgA nephropathy

A

Henoch-Schonlein vasculitis

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7
Q

Presence of IgA immune deposits in the glomerular mesangium

A

IgA nephropathy
Crohn’s disease
Dermatitis herpetiformis
Sjogren’s syndrome

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8
Q

Histopathologic lesion of IgA Nephropathy

A

Mesangioproliferative GN

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9
Q

“Sympharyngitic hematuria”

A

IgA Nephropathy

hematuria occurs during or immediately after the URTI

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10
Q

ANCA positive pauci-immune GN

A

Granulomatosis with polyangiitis (Wegener’s)
Churg-Strauss
Microscopic Polyangiitis

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11
Q

Anti PR3 ANCA commonly seen

A

Granulomatosis with polyangiitis (Wegener’s)

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12
Q

Anti MPO ANCA

A

Churg-Strauss

Microscopic polyangiitis

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13
Q

Anti PR3 + small vessel vasculitis + purulent rhinorrhea + nasal ulcers + sinus pain + polyarthritis + segmental necrotizing GN

A

Wegener’s

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14
Q

Anti MPO ANCA + small vessel vasculitis + peripheral eosinophilia + asthma + cutaneous purpura + mononeuritis + focal segmental necrotizing GN

A

Churg-Strauss

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15
Q

Hypocomplementemic form of GN + mixed nephritic and nephrotic features + assocated with Hep C infections, autoimmune diseases or neoplastic diseases

A

Type I MPGN

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16
Q

Histologic presentation of poststrep GN

A

Diffuse proliferative GN

17
Q

Histologic presentation of Hodgkin’s disease developing nephrotic syndrome

A

Minimal Change Disease

18
Q

GN most commonly associated with solid tumors and infections such as Hep B, malaria and schistosomiasis

A

Membranous GN

19
Q

MCC of nephrotic syndrome in the elderly

A

Membranous nephropathy

20
Q

Microalbuminuria

A

30-300 mg/24 hours

21
Q

AntiHPN of choice for T1DM with DMN

A

ACEI

T2DM: ARBS

22
Q

Renal lesion of HIVAN

23
Q

Most corticosteroid-responsibe GN causing nephrotic syndrome

A

Minimal change disease

24
Q

Histologic feature characteristic of malignant hypertension

A

Fibrinoid necrosis of small blood vessels

25
Acute glomerular injury associated with livedo reticularis, necrosis of toes, Hollenhorst plaques and eosinophilia due to cholesterol embolization
FSGS
26
Characteristic histopathologic feature of the thrombotic microangiopathies
Glomerular capillary endotheliosis with platelet thrombi
27
Thrombotic microangiopathy with predominant neurologic disturbances
Thrombotic thrombocytopenic purpura (TTP)
28
Associated with Hepatitis B
Membranoproliferative GN
29
MC renal lesion associated with Hep C
Cryoglobulinemic GN
30
Schistosoma MC associated with clinical renal disease
S.mansoni
31
Pulmonary-renal syndrome consists of lung hemorrhage in combination with anti-GBM nephritis often presenting as RPGN
Goodpasture's
32
MCC of nephrotic syndrome
Minimal Change Disease