Glomerulonephritis

Question 1

Clinicopathologic correlate of RPGN

Answer 1

Crescentic GN

Question 2

Pulmonary-renal syndrome consists of lung hemorrhage in combination with anti-GBM nephritis presenting as RPGN

Answer 2

Goodpasture’s

Question 3

“Flea-bitten” appearance of kidneys on gross pathology due to subcapsular hemorrhages

Answer 3

Subacute bacterial endocarditis

Question 4

GN occurring with IE, shunt infections or intraabdominal or pelvic abscesses

Answer 4

Immune complex GN

Question 5

MC GN worldwide

Answer 5

IgA nephropathy/Berger’s

Question 6

Vasculitis closely associated with IgA nephropathy

Answer 6

Henoch-Schonlein vasculitis

Question 7

Presence of IgA immune deposits in the glomerular mesangium

Answer 7

IgA nephropathy
Crohn’s disease
Dermatitis herpetiformis
Sjogren’s syndrome

Question 8

Histopathologic lesion of IgA Nephropathy

Answer 8

Mesangioproliferative GN

Question 9

“Sympharyngitic hematuria”

Answer 9

IgA Nephropathy

hematuria occurs during or immediately after the URTI

Question 10

ANCA positive pauci-immune GN

Answer 10

Granulomatosis with polyangiitis (Wegener’s)
Churg-Strauss
Microscopic Polyangiitis

Question 11

Anti PR3 ANCA commonly seen

Answer 11

Granulomatosis with polyangiitis (Wegener’s)

Question 12

Anti MPO ANCA

Answer 12

Churg-Strauss

Microscopic polyangiitis

Question 13

Anti PR3 + small vessel vasculitis + purulent rhinorrhea + nasal ulcers + sinus pain + polyarthritis + segmental necrotizing GN

Answer 13

Wegener’s

Question 14

Anti MPO ANCA + small vessel vasculitis + peripheral eosinophilia + asthma + cutaneous purpura + mononeuritis + focal segmental necrotizing GN

Answer 14

Churg-Strauss

Question 15

Hypocomplementemic form of GN + mixed nephritic and nephrotic features + assocated with Hep C infections, autoimmune diseases or neoplastic diseases

Answer 15

Type I MPGN

Question 16

Histologic presentation of poststrep GN

Answer 16

Diffuse proliferative GN

Question 17

Histologic presentation of Hodgkin’s disease developing nephrotic syndrome

Answer 17

Minimal Change Disease

Question 18

GN most commonly associated with solid tumors and infections such as Hep B, malaria and schistosomiasis

Answer 18

Membranous GN

Question 19

MCC of nephrotic syndrome in the elderly

Answer 19

Membranous nephropathy

Question 20

Microalbuminuria

Answer 20

30-300 mg/24 hours

Question 21

AntiHPN of choice for T1DM with DMN

Answer 21

ACEI

T2DM: ARBS

Question 22

Renal lesion of HIVAN

Answer 22

FSGS

Question 23

Most corticosteroid-responsibe GN causing nephrotic syndrome

Answer 23

Minimal change disease

Question 24

Histologic feature characteristic of malignant hypertension

Answer 24

Fibrinoid necrosis of small blood vessels

Question 25

Acute glomerular injury associated with livedo reticularis, necrosis of toes, Hollenhorst plaques and eosinophilia due to cholesterol embolization

Answer 25

FSGS

Question 26

Characteristic histopathologic feature of the thrombotic microangiopathies

Answer 26

Glomerular capillary endotheliosis with platelet thrombi

Question 27

Thrombotic microangiopathy with predominant neurologic disturbances

Answer 27

Thrombotic thrombocytopenic purpura (TTP)

Question 28

Associated with Hepatitis B

Answer 28

Membranoproliferative GN

Question 29

MC renal lesion associated with Hep C

Answer 29

Cryoglobulinemic GN

Question 30

Schistosoma MC associated with clinical renal disease

Answer 30

S.mansoni

Question 31

Pulmonary-renal syndrome consists of lung hemorrhage in combination with anti-GBM nephritis often presenting as RPGN

Answer 31

Goodpasture’s

Question 32

MCC of nephrotic syndrome

Answer 32

Minimal Change Disease