Glomerulonephritis Flashcards
0
Q
Consequences of glomerulonephritis
A
Increased glomerular permeability resulting in proteinuria and blood cells in urine
1
Q
Definition of glomerulonephritis
A
Inflammation of glomeruli
2
Q
Consequence of chronic glomerulonephritis
A
Damage to intercellular matrix resulting in fibrosis (scar formation), leads to chronic renal failure
3
Q
5 glomerular syndromes
A
- Nephritic syndrome
- Nephrotic syndrome
- Asymptomatic proteinuria
- Painless haematuria
- Chronic renal failure
4
Q
Features of nephritic syndrome
A
- Haematuria
- Hypertension
- Acute renal failure
5
Q
Features of nephrotic syndrome
A
- Marked proteinuria
- Hypoalbuminaemia
- Oedema
6
Q
Features of chronic renal failure
A
- Decreased GFR
- Uraemia
- Hypocalcaemia (& other electrolyte imbalance
- Anaemia
7
Q
Most common cause of nephrotic syndrome
A
Glomerulonephritis
8
Q
Underlying defect in nephrotic syndrome
A
Increased capillary permeability to proteins
9
Q
3 pathogenesis mechanisms of glomerulonephritis
A
- Deposition of circulating immune complexes
- Implanted antigens causing formation of immune complexes in situ
- Anti-glomerular basement membrane antibody present
