Glomerulonephritis Flashcards
What is it?
Inflammation and damage to the glomeruli
How can it present?
Nephrotic syndrome
Nephritic syndrome
Renal failure
What are the main characteristics of nephrotic syndrome?
Oedema
Hypoalbuminaemia
Hypercholesterolaemia
What are the causes of nephrotic syndrome?
Minimal change disease
Focal segmental glomerulosclerosis
Membranous nephropathy
What are the complications of nephrotic syndrome?
Infection VTE CKD Hypertension Hyperlipidaemia
How does nephritic syndrome present?
AKI
Urine dipstick - blood, protein
Mild to moderate oedema
Hypertension
What are the causes of nephritic syndrome?
Post streptococcal GN IgA nephropathy Small vessel vasculitis Goodpasture's syndrome Thin basement membrane disease Lupus nephritis
What is the management of glomerulonephritis?
Supportive - ACEi/ARB, control BP, salt and water restriction, diuretics, statins
Immunosuppressive therapy