Glom/Polycyst Kidneys Flashcards

1
Q

Renal pain usually where?

A

ipsilat CVA

can radiate to testes/labium

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2
Q

Ureteral pain usually from what?

A

result of obstruction

(U) acute

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3
Q

Vesical (bladder) pain usually from/where?

A

acute urinary retention

suprapubic

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4
Q

Prostatic pain usually from/where?

A

inflamm

perineum

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5
Q

Penile pain (U) from?

A

inflamm from STD

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6
Q

Testicular pain (U) from?

A

acute conditions (i.e. torsion)

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7
Q

Hematuria in adults considered what?

A

malignancy until proven otherwise

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8
Q

Initial Hematuria is?

(U) from?

A

blood at start of stream

(U) urethral

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9
Q

Terminal Hematuria is?

(U) from?

A

blood at end of stream

(U) bladder neck, prostate

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10
Q

GFR dependent on what? (2)

A

Permeability of capillary to water/solutes,

Surface area of capillary

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11
Q

GFR drops how much every year > 40?

A

1%

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12
Q

GFR rate?

A

Male: 125 ml/min
Female: 115 ml/min

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13
Q

Creatine made where/from?

A

liver

arginine/glycine

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14
Q

Creatine primarily stored where?

A

muscles (98%)

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15
Q

Urea is?

Made where/from?

A

Nitrogen-containing metabolite

liver
degration of protein

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16
Q

Urea prdxn depends on what? (3)

A

1) protein in diet
2) catabolic states
3) liver fxn

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17
Q

[Urea] response to renal dz-caused decrease in GFR how?

A

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18
Q

What drugs may cause Hematuria?

A
Anticoag
Analgesic abuse (papillary necrosis)
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19
Q

Volume overload categorized into what two things?

A

Obstructed venous return (venous stasis)

Systemic processes (CHF, cirrhosis, neph synd)

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20
Q

If edema goes away in the a.m., what is the cause?

A

venous stasis

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21
Q

Dehydration is?

Volume depletion is?

A

loss of pure H2O

loss of Na+ and H2O

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22
Q

Differentiate b/w dehyd and volm dep how?

A

check urine sodium

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23
Q

HypoNa+ is?

A

serum Na+ < 130

Most (C) electrolyte imbalance in hospitalized pts

24
Q

HypoNa+ clinical presentation?

A

↓ serum osmo w/ ↑ urine osmo
No cardiac/renal/liver dz
Normal thyroid/adrenal fxn

25
Asympt HypoNa+ tx?
SLOWLY H2O restriction Normal saline w/ Lasix (loop)
26
Hypertonic hypoNa+ U seen w/?
hyperglycemia
27
HyperNa+ U prevented by what mechanism?
thirst
28
HyperNa+ from dehydration presentation?
ortho hypoTN | oliguria
29
DI present w/ urine osmo of what?
< 250 + hyperNa+
30
HypoK+ presentation?
mm weakness, fatigue, cramps | Long T, U, depressed ST
31
HypoK+ tx?
oral/IV K+ | check Mg if not improving
32
HyperK+ presentation?
mm weakness, GI | Tall T, wide QRS
33
HyperK+ tx, first step?
Rerun test | Stop any K+ sparing/containing meds
34
HyperK+ tx, toxicity?
Insulin + D50W Abuterol Hemodialysis (if renal insuff)
35
HypoCa2+ is most C cause of what?
renal failure
36
HypoCa2+ presentation?
mm spasm Chovostek/Trousseau Wide QT
37
HypoCa2+ tx?
Oral/IV Ca2+
38
HyperCa2+ U caused by?
hyperPTH | *always check PTH levels!
39
HyperCa2+ presentation?
constipation, polyuria | stupor, coma
40
HyperCa2+ tx?
Saline + Lasix
41
HyperCa2+ tx if caused by malignancy?
bisphosphates
42
Glomerulonephritis classifications? (2)
1) Renal abnormalities only | 2) Caused by systemic dz (i.e. lupus, DM)
43
Glomerulonephritis U caused by?
Immune complexes (IgA nephropathy AKA Berger's)
44
Other causes of Glomerulonephritis?
Malig HTN | Hemolytic-Uremic synd
45
Glomerulonephritis lab results?
RED CELL CASTS hematuria proteinuria (precedes appearance of blood)
46
Berger's presents in adults? In children?
asympt microscopic (not visible) hematuria gross (visible) hematuria following URI
47
Henoch-Schonlein Purpura is? Presents as?
most C systemic vasculitis in kids IgA neph skin, arthralgia, GI
48
Glomerulonephritis caused by Group A beta-hemolytic Strep epidemiology? Lab results? Tx?
(U) kids, winter ASO titers supportive
49
Wegener's granulomatosis is? Lab results? Other sxs?
systemic vasculitis + ANCA pulmonary hemorrhage
50
Goodpasture's Synd is? Lab results? Other sxs?
systemic vasculitis Anti-glom basement memb antibody pulmonary hemoptysis
51
Glomerulonephritis physical exam findings?
``` COLA-COLORED URINE Red cell casts HTN Periorbital/Sacral edema Oliguria ```
52
Glomerulonephritis lab tests?
UA = red cell casts, (P) proteinuria Cr BUN Strep (ASO titer) Blood cx in febrile pts
53
Glomerulonephritis tx?
No Na+, K+ Fluid restrict Loops Steroids
54
Polycystic Kidney Disease epidemiology? Presentation?
20 - 40 yo 90% inherited Pain (most C complaint) Palpable flank mass HTN (reduced RAAS fxn) STONES
55
Polycystic Kidney Disease labs?
Hgb/Hct (anemia from ↓ erythropoietin pdx or from chronic dz) Electrolytes BUN, Cr UA (protein/blood) Erythropoietin
56
Polycystic Kidney Disease imaging?
Abd renal US
57
Polycystic Kidney Disease tx?
Stones: litho, IV/PO fluids HTN: ACE Avoid contact sports: rupture kidney cysts