Globular Protein

Question 1

Recessive disorders:

Answer 1

the two copies of the gene must be affected

Question 2

Dominant disorders :

Answer 2

affection of one copy of the gene

is enough to manifest the the disease.

Question 3

Cystic Fibrosis (CF)
 is ?

Answer 3

a single gene disorder

Question 4

What is the gene and chromosome of Cystic Fibrosis (CF) ?

Answer 4

(CFTR) gene on chromosome 7

Question 5

Cystic Fibrosis (CF) it is a !

Answer 5

recessive disease

Question 6

in the Cystic Fibrosis (CF) A normal product of this gene is ?

Answer 6

chloride channel

Question 7

The most common mutation of Cystic Fibrosis (CF)

, called ?

Answer 7

delta F508 (ΔF508)

Question 8

What is the function of delta F508 (ΔF508) ?

Answer 8

deletion of phenylalanine at position 508

Question 9

Cystic Fibrosis CF involves the accumulation of ?

Answer 9

thick mucus in the lungs and pancreatic ducts

Question 10

X-linked diseases they are ?

Answer 10

single gene disorders in which there is

defective genes on the X chromosome

Question 11

males always pass their X chromosome to their ?

Answer 11

daughters

Question 12

whereas females pass their X chromosomes ?

Answer 12

to both daughters and sons

Question 13

men affected by X-linked diseases never pass the

disease to their ?

Answer 13

sons

Question 14

Huntington’s disease is ?

Answer 14

rare inherited single gene disorder.

Question 15

Huntington’s disease requires ?

Answer 15

full nursing care.

Question 16

What is the chromosome of Huntington’s disease ?

Answer 16

Huntington’s disease

Question 17

Huntington’s disease is an ?

Answer 17

autosomal dominant disease

Question 18

Cystic Fibrosis (CF) is ?

Answer 18

recessive disease

Question 19

Fragile-X syndrome It is an inherited form of mental retardation caused by a ?

Answer 19

single malfunctioning gene on the X-chromosome.

Question 20

In the Fragile-X syndrome the Affected individuals usually have delayed development of
speech and language by ?

Answer 20

age 2

Question 21

UCA is given a different third base U instead of A to become UCU which is still codes for serine ?

Answer 21

Silent mutation

Question 22

changed base may code for a different amino acid.

Answer 22

Missense mutation

Question 23

serine codon UCA is given a different
first base—C—to become CCA, it will code for a
different amino acid, which is proline is ?

Answer 23

Missense mutation

Question 24

changed base may become a

termination codon ?

Answer 24

Nonsense mutation

Question 25

Physical appearance is called the ?

Answer 25

phenotype

Question 26

All daughters of an affected male and a normal female are ?

Answer 26

carriers

Question 27

All sons of an affected male and a normal female are ?

Answer 27

normal

Question 28

This type of inheritance of Mitochondrial also known as ?

Answer 28

maternal inheritance