glands 1 Flashcards
what is a gland
an epithelial cell or an aggregate of epithelial cells that are specialised for the secretion of a substance
what are the differences between endocrine and exocrine glands
endocrine glands are ductless and exocrine are ducted
endocrine secrete directly into blood flowing through them to let the secretion function at distant parts of the body. They secrete hormones.
exocrine glands secrete Into a location of the body through a duct and their secretions are enzymes or lubricants. only cells in the apex of the duct secret the products whereas in endocrine all epithelial cells secrete the hormones.
Examples of endocrine glands
pituitary gland
thyroid gland
parathyroid gland
examples of exocrine glands
salivary gland pancreas-amylase,trypsin,lipase mammary sweat glands sebaceous gland lachrymal gland- water and lysozyme in eye
how are glands generated in utero
1) growth signal received (from mesenchymal stem cells)
2) proliferation of cells occur and extracellular protein degradation enzymes are produced
3) epithelial cells invade space created
4) exocrine gland:central cells die off to produce duct (canalicularisation)
5) endocrine- produce angiogenic factors to stimulate blood vessel growth in and around the epithelial cells
what are the different shapes of gland ducts
simple tubular simple branched tubular compound tubular simple alveolar simple branched alveolar compound alveolar compound tubuloalveolar
what are myoepithelial cells
cells that have features of an epithelial cell and muscle cell
what is another word for acinar
alveolar
how can glands be classified in terms of mode of secretion
merocrine
apocrine
holocrine
how does merocrine secretion work and what are its two pathways
fusion of vesicles with apical membrane (form of exocytosis)
1) regulated secretion -secretory granules accumulate in large vesicles and are released by exostosis upon stimulation (needs ca2+), uses ATP
2) constitutive secretion- secretary. product is not concentrated into granules but packaged into small vesicles
what is apocrine secretion
partial loss of cytoplasm
what is holocrine secretion
complete loss of cytoplasm or cell
what is a cytocrine secretion
when the cell is released as a secretion
e.g spermatid