glands 1 Flashcards

1
Q

what is a gland

A

an epithelial cell or an aggregate of epithelial cells that are specialised for the secretion of a substance

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2
Q

what are the differences between endocrine and exocrine glands

A

endocrine glands are ductless and exocrine are ducted
endocrine secrete directly into blood flowing through them to let the secretion function at distant parts of the body. They secrete hormones.
exocrine glands secrete Into a location of the body through a duct and their secretions are enzymes or lubricants. only cells in the apex of the duct secret the products whereas in endocrine all epithelial cells secrete the hormones.

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3
Q

Examples of endocrine glands

A

pituitary gland
thyroid gland
parathyroid gland

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4
Q

examples of exocrine glands

A
salivary gland 
pancreas-amylase,trypsin,lipase
mammary 
sweat glands 
sebaceous gland 
lachrymal gland- water and lysozyme in eye
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5
Q

how are glands generated in utero

A

1) growth signal received (from mesenchymal stem cells)
2) proliferation of cells occur and extracellular protein degradation enzymes are produced
3) epithelial cells invade space created
4) exocrine gland:central cells die off to produce duct (canalicularisation)
5) endocrine- produce angiogenic factors to stimulate blood vessel growth in and around the epithelial cells

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6
Q

what are the different shapes of gland ducts

A
simple tubular
simple branched tubular 
compound tubular 
simple alveolar 
simple branched alveolar 
compound alveolar 
compound tubuloalveolar
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7
Q

what are myoepithelial cells

A

cells that have features of an epithelial cell and muscle cell

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8
Q

what is another word for acinar

A

alveolar

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9
Q

how can glands be classified in terms of mode of secretion

A

merocrine
apocrine
holocrine

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10
Q

how does merocrine secretion work and what are its two pathways

A

fusion of vesicles with apical membrane (form of exocytosis)

1) regulated secretion -secretory granules accumulate in large vesicles and are released by exostosis upon stimulation (needs ca2+), uses ATP
2) constitutive secretion- secretary. product is not concentrated into granules but packaged into small vesicles

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11
Q

what is apocrine secretion

A

partial loss of cytoplasm

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12
Q

what is holocrine secretion

A

complete loss of cytoplasm or cell

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13
Q

what is a cytocrine secretion

A

when the cell is released as a secretion

e.g spermatid

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