GIT- Warm Up Flashcards
@#e 1. The following statements regarding acute pancreatitis are true: (T/F)
a) Mumps is a recognized cause
b) Pancreatic oedema is a late sign
c) Pancreatic necrosis demonstrated on CT is associated with a mortality of 5-10%
d) Right-sided pleural effusion is seen in 5%
e) Haemorrhagic pancreatitis is diagnosed by the presence of hypodense areas of 5-20 Hounsfield units on CT
1.
a) True - alcohol and gallstones are commonest
b) False - this is the earliest sign
c) False - there is a mortality of more than 20%
d) False-left-sided
e) False - hyperdense areas of 50-70 Hounsfield units
@# Regarding hepatocellular carcinoma: (T/F)
a) It is the commonest primary visceral malignancy in the world
b) Haemochromatosis is a recognized cause
c) Elevated alpha-fetoprotein is found in 50-60% of cases
d) Has a higher incidence in macronodular than micronodular cirrhosis
e) On MR, hepatoma has a well defined, hypointense capsule on T1 weighted images
a) True
b) True - other causes are cirrhosis, hepatitis, alpha-1 antitrypsin deficiency, Wilson’s disease, aflatoxin, thorotrast
c) False-90%
d) True
e) False - increased signal intensity on a T2 weighted image. Peripheral gadolinium enhancement is seen in about 20%
@# 3. The following are true of positron emission tomography (PET): (T/F)
a) Noise is higher than in single-photon emission computed tomography
b) Detectors are made of bismuth germinate
c) Resolution is better than in SPECT
d) The effective dose is much higher than in routine gamma imaging
e) It is reliant on the release of gamma rays
3.
a) False - lower
b) True
c) True
d) False
e) False-positive beta particle emission
- Regarding MRI of the liver: (T/F)
a) Fast spin echo involves a series of 180 degree refocusing pulses after the initial 90 degree pulse
b) Hepatocellular carcinoma is best demonstrated 20-30 seconds after contrast injection on a Tl weighted gadolinium-enhanced image
c) Haemangiomas are of uniform low signal on T1 weighted MRI
d) Dynamic imaging of haemangiomas shows a dense peripheral nodular blush during the arterial phase of liver perfusion
e) Hepatocellular carcinoma is usually hypointense on T2 weighted MRI
4.
a) True
b) True
c) True
d) True - though small haemangiomas have a uniform immediate enhancement pattern of the whole lesion
e) False - increased signal intensity on T2 weighted images and reduced signal on TI
@#e 5. The following statements regarding pancreatic carcinoma are true: (T/F)
a) 60-70% of pancreatic carcinomas arise in the tail
b) They are usually hypovascular
c) Calcification is common
d) Contiguous organ invasion is rare
e) On ultrasound appears as a hyperechoic pancreatic mass
5.
a) False - 60-70% in the head, 30% body and 10% in the tail
b) True
c) False - about 2%
d) False - 40% invade oesophagus, stomach, duodenum
e) False - hypoechoic
- Regarding pancreatic islet cell tumours: (T/F)
a) Glucagonoma is the commonest functioning islet cell tumour
b) Insulinoma is found predominantly in the pancreatic body and tail
c) Glucagonoma is a hypervascular tumour
d) Glucagonoma undergoes malignant transformation in 5-10%
e) Multiple insulinomas are associated with MEN Type 1
6.
a) False - insulinoma
b) False - glucagonoma. Insulinoma has no predilection for any part
c) True - 90% of glucagonomas are hypervascular. 66% of insulinomas
d) False - insulinoma. 80% glucagonomas undergo malignant transformation. 50% have liver metastases at diagnosis
e) True
@#e 7. Regarding porcelain gallbladder: (T/F)
a) It is often symptomless
b) It is rarely associated with gallstones
c) Oral cholecystogram shows a non-functioning gallbladder
d) 60-70% develop carcinoma of the gallbladder
e) Acute pancreatitis is a recognized cause
7.
a) True
b) False - 90%
c) True
d) False 10-20%
e) False
- Regarding pancreatic cysts: (T/F)
a) 70-80% of pancreatic cysts are pseudocysts
b) 10% of patients with autosomal dominant polycystic kidney disease have associated pancreatic cysts
c) Pancreatic pseudocysts can occur in the posterior mediastinum
d) Serous cystadenoma is a common malignant tumour found in children
e) Persistent cysts exceeding 5 cm in diameter require drainage
8.
a) True -25% are true cysts, i.e retention/dermoid/malignant cysts
b) True - in von Hippel-Lindau syndrome pancreatic cysts are present in more than 50%
c) True - most commonly found in the lesser sac but can be found in the inguinal region and mediastinum
d) False - benign tumour of elderly women which has a characteristic sunburst calcified appearance with a central fibrotic scar
e) True- to prevent complications of rupture/infection/haemorrhage
@#e 9. The following statements regarding splenic lymphoma are true: (T/F)
a) The spleen is involved at presentation in 30-40% of patients with non-Hodgkin’s lymphoma
b) Focal splenic deposits are usually well defined, round lesions of increased brightness on ultrasound
c) When there is lymphomatous involvement of the spleen, splenomegaly is seen in 70-80%
d) Splenic lymphoma deposits commonly calcify
e) Lymph nodes are seen in the splenic hilum in 50% of patients with Hodgkin’s lymphoma
9.
a) True - slightly higher for Hodgkin’s lymphoma
b) False - reduced echogenicity
c) False -50%
d) True
e) False - uncommon
@# 10. The following are features of extrahepatic cholangiocarcinoma: (T/F)
a) It accounts for 10-15% of all cholangiocarcinomas
b) Is most commonly identified in children under 6 years old
c) Inflammatory bowel disease increases the risk by 2 times
d) Most commonly found in the cystic duct
e) Hypovascular on angiography
10.
a) False - extrahepatic is commoner accounting for 90%
b) False - 50-60-year-olds
c) False - 10 times increased risk. Other predisposing factors include sclerosing cholangitis, Caroli’s disease, thorotrast exposure, alpha-1 antitrypsin deficiency and autosomal
dominant polycystic kidney disease
d) False - most commonly involves the common bile duct
e) False - hypervascular tumour
@# 11. Features of the MEN II syndrome (Sipple’s syndrome) include: (T/F)
a) Insulinoma
b) Phaeochromocytoma
c) Hyperparathyroidism
d) Medullary carcinoma of the thyroid
e) Pituitary adenoma
11.
a) False
b) True
c) True
d) True
e) False
- Liver lesions which appear echogenic on ultrasound include: (T/F)
a) Lymphoma
b) Cervical cancer metastases
c) Colonic carcinoma metastases
d) Hepatoma
e) Treated breast cancer metastases
12.
a) False
b) False
c) True
d) True
e) True
- The following are causes of generalised increase in liver echogenicity on ultrasound: (T/F)
a) Fatty infiltration
b) Cirrhosis
c) Lymphoma
d) Chronic hepatitis
e) Vacuolar degeneration
13.
a) True
b) True
c) False
d) True
e) True
@#e 14. Regarding Budd-Chiari syndrome: (T/F)
a) It can be caused by obstruction of the suprahepatic IVC
b) On early CT images, the central liver enhances prominently and the peripheral liver weakly
c) The caudate lobe is markedly atrophic
d) On MRI images ‘comma-shaped’ intrahepatic collateral vessels are seen
f) A ‘spider’s web’ appearance at hepatic venography is characteristic
14.
a) True - this is primary obstruction. Secondary obstructions commoner and are due to thrombosis in hepatic veins
b) True - ‘flip-flop’ pattern. On late images the central liver has washed out and peripherally there is enhancement
c) False - caudate lobe is enlarged
d) True
e) True
- Features of portal hypertension include: (T/F)
a) Portal vein diameter of> 13 mm
b) Splenomegaly
c) Reduction in portal vein velocities to 7-12 cm/s
d) Schistosomiasis is a recognized cause
e) Loss of portal venous flow in expiration
15.
a) True
b) True
c) True
d) True
e) True
- Features of focal nodular hyperplasia (FNH) include: (T/F)
a) Hypovascular
b) Necrosis and haemorrhage are common
c) 80-90% of tumours are multiple
d) A strong association with oral contraceptive use
e) 50-70% show reduced activity on technetium sulphur colloid scanning
16.
a) False-hypervascular
b) False - rare in FNH but common in hepatic adenoma
c) False - solitary
d) False - no association. Hepatic adenoma is associated
e) False - 50-70% normal or increased activity
- Splenic hamartomas are: (T/F)
a) Usually associated with hamartomas in other locations
b) The most common primary splenic tumour
c) of reduced attenuation on unenhanced CT
d) of heterogenous increased signal intensity on T2 weighted MRI images
e) Associated with Turner’s syndrome
17.
a) True
b) False - rare non-neoplastic lesion
c) True
d) True
e) False - splenic haemangiomas are associated
- Features of hydatid disease of the liver include: (T/F)
a) Raised blood eosinophilia count
b) Left lobe is more commonly affected than the right lobe
c) Rarely calcifies
d) On ultrasound, appearances of a heterogenous mass with daughter cysts
e) Communication with right hepatic duct in 50-60%
18.
a) True
b) False - right lobe more than the left. Multiple in 20%
c) False - peripheral calcification in 20-30%. Eggshell calcification in the cyst wall is a rare appearance
d) True
e) True - left hepatic duct in 30%. Common hepatic duct in 10%
- Epidermoid cysts of the spleen: (T/F)
a) Are multiple in 80%
b) Are usually < 1 cm in size
c) Peripheral septations are extremely rare
d) Central calcification is seen in 70-80%
e) Are associated with autosomal dominant polycystic kidney disease
19.
a) False - solitary in 80%
b) False- usually 10 cm in size
c) False - found in 85%
d) False - calcification in the wall is seen in 10-20%
e) True
- The following statements are true: (T/F)
a) Hepatic veins have no valves
b) Ligamentum teres is the obliterated remnant of the umbilical artery
c) The portal vein is formed by the inferior mesenteric vein and splenic vein
d) Hepatic veins drain to the IVC without an extrahepatic course
e) In the Couinaud system - segment 2 and 4a are divided by the left hepatic vein
20.
a) True
b) False - left umbilical vein
c) False - superior mesenteric vein and splenic vein
d) True
e) True